Ectodysplasin A2 Receptor Protein (EDA2R) (AA 1-138) (His tag)

Produktnummer ABIN5853331

Produktdetails

Target: Ectodysplasin A2 Receptor (EDA2R)

Protein-Typ: Recombinant

Proteineigenschaft: AA 1-138

Spezies: Human

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses Ectodysplasin A2 Receptor Protein ist gelabelt mit His tag.

Applikation: SDS-PAGE (SDS)

Sequenz: MGSSHHHHHH SSGLVPRGSH MGSMDCQENE YWDQWGRCVT CQRCGPGQEL SKDCGYGEGG DAYCTACPPR RYKSSWGHHR CQSCITCAVI NRVQKVNCTA TSNAVCGDCL PRFYRKTRIG GLQDQECIPC TKQTPTSEVQ CAFQLSLVEA DAPTVPPQEA T

Reinheit: > 90 % by SDS - PAGE

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

Denatured

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid. 20  mM Tris-HCl buffer (  pH 8.0) containing 10 % glycerol 0.4M urea

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.

Antigendetails

Target: Ectodysplasin A2 Receptor (EDA2R)

Andere Bezeichnung: EDA2R (EDA2R Produkte)

Synonyme: EDA-A2R Protein, EDAA2R Protein, TNFRSF27 Protein, XEDAR Protein, 9430060M22Rik Protein, Xedar Protein, RGD1564025 Protein, ectodysplasin A2 receptor Protein, EDA2R Protein, Eda2r Protein

Hintergrund: EDA-A1 and EDA-A2 are two isoforms of ectodysplasin that are encoded by the anhidrotic ectodermal dysplasia (EDA) gene. Mutations in EDA give rise to a clinical syndrome characterized by loss of hair, sweat glands, and teeth. EDA2R specifically binds to EDA-A2 isoform. This protein is a type III transmembrane protein of the TNFR (tumor necrosis factor receptor) superfamily, and contains 3 cysteine-rich repeats and a single transmembrane domain but lacks an N-terminal signal peptide. Alternatively spliced transcript variants have been found for this gene. Recombinant human EDA2R protein , fused to His-tag at N-terminus, was expressed in E.coli.

Molekulargewicht: 17.7 kDa (161aa)

NCBI Accession: NP_001229239

UniProt: Q9HAV5