QKI Protein (AA 1-341) (His tag)

Produktnummer ABIN5853304

Produktdetails

Target: QKI (Protein Quaking (QKI))

Protein-Typ: Recombinant

Proteineigenschaft: AA 1-341

Spezies: Human

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses QKI Protein ist gelabelt mit His tag.

Applikation: SDS-PAGE (SDS)

Sequenz: MGSSHHHHHH SSGLVPRGSH MGSMVGEMET KEKPKPTPDY LMQLMNDKKL MSSLPNFCGI FNHLERLLDE EISRVRKDMY NDTLNGSTEK RSAELPDAVG PIVQLQEKLY VPVKEYPDFN FVGRILGPRG LTAKQLEAET GCKIMVRGKG SMRDKKKEEQ NRGKPNWEHL NEDLHVLITV EDAQNRAEIK LKRAVEEVKK LLVPAAEGED SLKKMQLMEL AILNGTYRDA NIKSPALAFS LAATAQAAPR IITGPAPVLP PAALRTPTPA GPTIMPLIRQ IQTAVMPNGT PHPTAAIVPP GPEAGLIYTP YEYPYTLAPA TSILEYPIEP SGVLGAVATK VRRHDMRVHP YQRIVTADRA ATGN

Reinheit: > 85 % by SDS - PAGE

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.25 mg/mL

Buffer: Liquid. In 20  mM Tris-HCl buffer (  pH 8.0) containing 0.2M NaCl, 50 % glycerol, 2  mM DTT

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.

Antigendetails

Target: QKI (Protein Quaking (QKI))

Andere Bezeichnung: QKI (QKI Produkte)

Synonyme: Hqk Protein, QK Protein, QK1 Protein, QK3 Protein, hqkI Protein, 1110003F05Rik Protein, 1500005P18 Protein, QkI Protein, l(17)-1Wis Protein, l17Wis1 Protein, Qki Protein, CQKI Protein, QKI-5 Protein, PqkI Protein, BqkI Protein, qk Protein, qk1 Protein, quaking Protein, Xqua Protein, qki Protein, EQKI Protein, EqkI Protein, QKI, KH domain containing RNA binding Protein, quaking Protein, QKI, KH domain containing, RNA binding S homeolog Protein, QKI, KH domain containing, RNA binding L homeolog Protein, QKI Protein, Qk Protein, qki.S Protein, qki.L Protein, Qki Protein

Hintergrund: Protein quaking isoform HQK-5, also known as QKI, is an RNA-binding protein that regulates pre-mRNA splicing, export of mRNAs from the nucleus, protein translation, and mRNA stability. It is involved in myelinization and oligodendrocyte differentiation, and it may play a role in schizophrenia. Defects or deletions in the QKI are associated with astrocytic tumors and may be involved in the pathogenesis of schizophrenia. Recombinant human QKI protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Molekulargewicht: 40.1 kDa (364aa) confirmed by MALDI-TOF

NCBI Accession: NP_006766

UniProt: Q96PU8