UBE2R2 Protein (AA 1-238) (His tag)

Produktnummer ABIN5853300

Produktdetails

Target: UBE2R2 (Ubiquitin-Conjugating Enzyme E2R 2 (UBE2R2))

Protein-Typ: Recombinant

Proteineigenschaft: AA 1-238

Spezies: Human

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses UBE2R2 Protein ist gelabelt mit His tag.

Applikation: SDS-PAGE (SDS)

Sequenz: MGSSHHHHHH SSGLVPRGSH MGSMAQQQMT SSQKALMLEL KSLQEEPVEG FRITLVDESD LYNWEVAIFG PPNTLYEGGY FKAHIKFPID YPYSPPTFRF LTKMWHPNIY ENGDVCISIL HPPVDDPQSG ELPSERWNPT QNVRTILLSV ISLLNEPNTF SPANVDASVM FRKWRDSKGK DKEYAEIIRK QVSATKAEAE KDGVKVPTTL AEYCIKTKVP SNDNSSDLLY DDLYDDDIDD EDEEEEDADC YDDDDSGNEE S

Reinheit: > 85 % by SDS - PAGE

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.25 mg/mL

Buffer: Liquid. In 20  mM Tris-HCl buffer (  pH 8.0) containing 0.15M NaCl, 20 % glycerol, 1  mM DTT

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.

Antigendetails

Target: UBE2R2 (Ubiquitin-Conjugating Enzyme E2R 2 (UBE2R2))

Andere Bezeichnung: uBE2R2 (UBE2R2 Produkte)

Synonyme: CDC34B Protein, E2-CDC34B Protein, UBC3B Protein, zgc:92307 Protein, UBE2R2 Protein, 1200003M11Rik Protein, Cdc34b Protein, Ubc3b Protein, cdc34b Protein, e2-cdc34b Protein, ubc3b Protein, ubiquitin conjugating enzyme E2 R2 Protein, ubiquitin-conjugating enzyme E2R 2 Protein, ubiquitin-conjugating enzyme E2R 2 pseudogene Protein, UBE2R2 Protein, ube2r2 Protein, LOC465050 Protein, Ube2r2 Protein

Hintergrund: UBE2R2 is a ubiquitous and pleiotropic Ser/Thr protein kinase involved in cell growth and transformation. This protein is a protein similar to the E2 ubiquitin conjugating enzyme uBC3/CDC34. Studies suggest that CK2-dependent phosphorylation of this ubiquitin-conjugating enzyme functions by regulating beta-TrCP substrate recognition and induces its interaction with beta-TrCP, enhancing beta-catenin degradation. Recombinant human uBE2R2 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Molekulargewicht: 29.6kDa (261aa) confirmed by MALDI-TOF (Molecular size on SDS-PAGE will appear higher)

NCBI Accession: NP_060281

UniProt: Q712K3