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RNF7 Protein (AA 1-113) (His tag)

RNF7 Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant > 90 % by SDS - PAGE SDS
Produktnummer ABIN5853188
  • Target Alle RNF7 Proteine anzeigen
    RNF7 (Ring Finger Protein 7 (RNF7))
    Protein-Typ
    Recombinant
    Proteineigenschaft
    AA 1-113
    Spezies
    • 5
    • 1
    Human
    Quelle
    • 2
    • 1
    • 1
    • 1
    • 1
    Escherichia coli (E. coli)
    Aufreinigungstag / Konjugat
    Dieses RNF7 Protein ist gelabelt mit His tag.
    Applikation
    SDS-PAGE (SDS)
    Sequenz
    MGSSHHHHHH SSGLVPRGSH MGSMADVEDG EETCALASHS GSSGSKSGGD KMFSLKKWNA VAMWSWDVEC DTCAICRVQV MDACLRCQAE NKQEDCVVVW GECNHSFHNC CMSLWVKQNN RCPLCQQDWV VQRIGK
    Reinheit
    > 90 % by SDS - PAGE
    Top Product
    Discover our top product RNF7 Protein
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Kommentare

    Denatured

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1.0 mg/mL
    Buffer
    Liquid. In 20  mM Tris-HCl buffer (  pH 8.0) containing 10 % glycerol, 0.4M urea
    Lagerung
    4 °C,-20 °C,-80 °C
    Informationen zur Lagerung
    Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
  • Target
    RNF7 (Ring Finger Protein 7 (RNF7))
    Andere Bezeichnung
    RNF7 (RNF7 Produkte)
    Synonyme
    CKBBP1 Protein, ROC2 Protein, SAG Protein, Rbx2 Protein, ring finger protein 7 Protein, RNF7 Protein, Rnf7 Protein
    Hintergrund
    RNF7 is a highly conserved ring finger protein. It is an essential subunit of SKP1-cullin/CDC53-F box protein ubiquitin ligases, which are a part of the protein degradation machinery important for cell cycle progression and signal transduction. This protein interacts with, and is a substrate of, casein kinase II (CSNK2A1/CKII). The phosphorylation of this protein by CSNK2A1 has been shown to promote the degradation of IkappaBalpha (CHuK/IKK-alpha/IKBKA) and p27Kip1(CDKN1B). Alternatively spliced transcript variants encoding distinct isoforms have been reported. Recombinant human RNF7 protein, fused to His-tag at N-terminus, was expressed in E.coli .
    Molekulargewicht
    15.1 kDa (136aa)
    NCBI Accession
    NP_055060
    UniProt
    Q9UBF6
    Pathways
    Positive Regulation of Endopeptidase Activity
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