MPZL1 Protein (AA 38-162) (His tag)
-
- Target Alle MPZL1 Proteine anzeigen
- MPZL1 (Myelin Protein Zero-Like 1 (MPZL1))
- Protein-Typ
- Recombinant
- Proteineigenschaft
- AA 38-162
-
Spezies
- Human
-
Quelle
- Escherichia coli (E. coli)
- Aufreinigungstag / Konjugat
- Dieses MPZL1 Protein ist gelabelt mit His tag.
- Applikation
- SDS-PAGE (SDS)
- Sequenz
- MGSSHHHHHH SSGLVPRGSH MGSLEVYTPK EIFVANGTQG KLTCKFKSTS TTGGLTSVSW SFQPEGADTT VSFFHYSQGQ VYLGNYPPFK DRISWAGDLD KKDASINIEN MQFIHNGTYI CDVKNPPDIV VQPGHIRLYV VEKENLPV
- Reinheit
- > 90 % by SDS - PAGE
- Top Product
- Discover our top product MPZL1 Protein
-
-
- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Format
- Liquid
- Konzentration
- 0.5 mg/mL
- Buffer
- Liquid. In 20 mM Tris-HCl buffer ( pH 8.0) containing 0.15M NaCl, 20 % glycerol, 1 mM DTT
- Lagerung
- 4 °C,-20 °C,-80 °C
- Informationen zur Lagerung
- Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
-
- Target
- MPZL1 (Myelin Protein Zero-Like 1 (MPZL1))
- Andere Bezeichnung
- MPZL1 (MPZL1 Produkte)
- Synonyme
- MPZL1 Protein, MPZL1b Protein, PZR Protein, PZR1b Protein, PZRa Protein, PZRb Protein, 1110007A10Rik Protein, myelin protein zero like 1 Protein, myelin protein zero-like 1 Protein, MPZL1 Protein, Mpzl1 Protein
- Hintergrund
- MPZL1 is a cell surface receptor, which is involved in signal transduction processes. This protein recruits PTPN11/SHP-2 to the cell membrane and is a putative substrate of PTPN11/SHP-2. It is a major receptor for concanavalin-A (ConA) and is involved in cellular signaling induced by ConA, which probably includes Src family tyrosine-protein kinases. Isoform 3 seems to have a dominant negative role, it blocks tyrosine phosphorylation of MPZL1 induced by ConA. Isoform 1, but not isoform 2 and isoform 3, may be involved in regulation of integrin-mediated cell motility. Recombinant human MPZL1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
- Molekulargewicht
- 16.1 kDa (148aa), confirmed by MALDI-TOF
- NCBI Accession
- NP_078845
- UniProt
- O95297
-