Crystallography grade
FAM84A
Spezies: Human
Wirt: Insektenzellen
Recombinant
>95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot.
ELISA, WB, SDS, Crys
2310003N02Rik Protein, 4731402F03Rik Protein, AW125753 Protein, Nse1 Protein, NSE1 Protein, PP11517 Protein, RGD1305779 Protein, zgc:63724 Protein, family with sequence similarity 84, member A Protein, family with sequence similarity 84 member A Protein, Fam84a Protein, FAM84A Protein, fam84a Protein
Hintergrund
FAM84A belongs to the FAM84 family of proteins and is predominantly expressed in testis. FAM84A localizes to a subcellular membrane region where there is no contact between neighboring cells and is believed to play a role in cell morphology and motility. More specifically, the expression of FAM84A increases cell motility. FAM84A is up-regulated in colorectal cancer lung cancer, pancreatic cancer, cholangiocarcinoma and bladder cancer tissues. Via its ability to increase cell motility, FAM84A may contribute to the invasion and metastasis of cancer cells. Recombinant human FAM84A protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.