LY86 Protein (AA 21-162) (His tag)

Produktnummer ABIN5853100

Produktdetails

Target: LY86 (Lymphocyte Antigen 86 (LY86))

Protein-Typ: Recombinant

Proteineigenschaft: AA 21-162

Spezies: Human

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses LY86 Protein ist gelabelt mit His tag.

Applikation: SDS-PAGE (SDS)

Sequenz: MGSSHHHHHH SSGLVPRGSH MGSGGGGKAW PTHVVCSDSG LEVLYQSCDP LQDFGFSVEK CSKQLKSNIN IRFGIILRED IKELFLDLAL MSQGSSVLNF SYPICEAALP KFSFCGRRKG EQIYYAGPVN NPEFTIPQGE YQVLLELYTE KRSTVACANA TIMCS

Reinheit: > 85 % by SDS - PAGE

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

Denatured

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid. In 20  mM Tris-HCl buffer (  pH 8.0) containing, 10 % glycerol, 0.4M urea

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.

Antigendetails

Target: LY86 (Lymphocyte Antigen 86 (LY86))

Andere Bezeichnung: LY86 (LY86 Produkte)

Synonyme: MD-1 Protein, MMD-1 Protein, dJ80N2.1 Protein, MD1 Protein, LY86 Protein, lymphocyte antigen 86 Protein, LY86 Protein, Ly86 Protein

Hintergrund: LY86 is highly expressed in B-cells, monocytes and tonsil. This protein may cooperate with CD180 and TLR4 to mediate the innate immune response to bacterial lipopolysaccharide (LPS) and cytokine production. It is important for efficient CD180 cell surface expression. Recombinant human LY86 protein, fused to His-tag at N-terminus, was expressed in E.coli .

Molekulargewicht: 18.1kDa (165aa)

NCBI Accession: NP_004262

UniProt: O95711

Pathways: Toll-Like Receptors Cascades