CNOT8 Protein (AA 1-292) (His tag)

Produktnummer ABIN5853036

Produktdetails

Target: CNOT8 (CCR4-NOT Transcription Complex, Subunit 8 (CNOT8))

Protein-Typ: Recombinant

Proteineigenschaft: AA 1-292

Spezies: Human

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses CNOT8 Protein ist gelabelt mit His tag.

Applikation: SDS-PAGE (SDS)

Sequenz: MGSSHHHHHH SSGLVPRGSH MGSMPAALVE NSQVICEVWA SNLEEEMRKI REIVLSYSYI AMDTEFPGVV VRPIGEFRSS IDYQYQLLRC NVDLLKIIQL GLTFTNEKGE YPSGINTWQF NFKFNLTEDM YSQDSIDLLA NSGLQFQKHE EEGIDTLHFA ELLMTSGVVL CDNVKWLSFH SGYDFGYMVK LLTDSRLPEE EHEFFHILNL FFPSIYDVKY LMKSCKNLKG GLQEVADQLD LQRIGRQHQA GSDSLLTGMA FFRMKELFFE DSIDDAKYCG RLYGLGTGVA QKQNEDVDSA QEKMSILAII NNMQQ

Reinheit: > 90 % by SDS - PAGE

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.25 mg/mL

Buffer: Liquid. In 20  mM Tris-HCl buffer (  pH 8.0) containing 0.15M NaCl, 10 % glycerol, 1  mM DTT

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.

Antigendetails

Target: CNOT8 (CCR4-NOT Transcription Complex, Subunit 8 (CNOT8))

Andere Bezeichnung: CNOT8 (CNOT8 Produkte)

Synonyme: calif Protein, pop2 Protein, zgc:63844 Protein, wu:fe49a05 Protein, caf1 Protein, hcaf1 Protein, CAF1 Protein, CALIF Protein, Caf1b Protein, POP2 Protein, hCAF1 Protein, 1500015I04Rik Protein, 1810022F04Rik Protein, AA536816 Protein, AU015770 Protein, AU043059 Protein, CCR4-NOT transcription complex, subunit 8 Protein, CCR4-NOT transcription complex subunit 8 Protein, CCR4-NOT transcription complex subunit 8 S homeolog Protein, Cnot8 Protein, CNOT8 Protein, cnot8.S Protein, cnot8 Protein, PAAG_04884 Protein, VDBG_08730 Protein

Hintergrund: CNOT8 belongs to the CAF1 family. It is a ubiquitous transcription factor required for a diverse set of processes and functions as part of the CCR-NOT complex. The CCR4-NOT complex functions as general transcription regulation complex. This complex contains CHAF1A, CHAF1B, CNOT1, CNOT2, CNOT3, CNOT4, CNOT6 and CNOT8 and binds BTG2. Recombinant human CNOT8 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Molekulargewicht: 35.9 kDa (315aa), confirmed by MALDI-TOF

NCBI Accession: NP_004770

UniProt: Q9UFF9