C1D Protein (AA 1-141) (His tag)

Produktnummer ABIN5853022

Produktdetails

Target: C1D (C1D Nuclear Receptor Corepressor (C1D))

Protein-Typ: Recombinant

Proteineigenschaft: AA 1-141

Spezies: Human

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses C1D Protein ist gelabelt mit His tag.

Applikation: SDS-PAGE (SDS)

Sequenz: MGSSHHHHHH SSGLVPRGSH MGSMAGEEIN EDYPVEIHEY LSAFENSIGA VDEMLKTMMS VSRNELLQKL DPLEQAKVDL VSAYTLNSMF WVYLATQGVN PKEHPVKQEL ERIRVYMNRV KEITDKKKAG KLDRGAASRF VKNALWEPKS KNASKVANKG KSKS

Reinheit: > 85 % by SDS - PAGE

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Liquid. In 20  mM Tris-HCl buffer (  pH 8.0) containing 0.2M NaCl, 50 % glycerol, 2  mM DTT

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.

Antigendetails

Target: C1D (C1D Nuclear Receptor Corepressor (C1D))

Andere Bezeichnung: C1D (C1D Produkte)

Synonyme: LRP1 Protein, SUN-CoR Protein, SUNCOR Protein, hC1D Protein, 1110036E10Rik Protein, AI875855 Protein, zgc:103509 Protein, RGD1560600 Protein, C1D nuclear receptor corepressor Protein, C1D nuclear receptor corepressor L homeolog Protein, C1D nuclear receptor co-repressor Protein, C1D Protein, c1d Protein, c1d.L Protein, C1d Protein

Hintergrund: Nuclear nucleic acid-binding protein C1D, also known as C1D, plays a role in the recruitment of the RNA exosome complex to pre-rRNA to mediate the 3'-5' end processing of the 5.8S rRNA, this function may include MPHOSPH6. This protein can activate PRKDC not only in the presence of linear DNA but also in the presence of supercoiled DNA. This protein can induce apoptosis in a p53/TP53 dependent manner. Recombinant human C1D protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Molekulargewicht: 18.4kDa (164aa), confirmed by MALDI-TOF

NCBI Accession: NP_775269

UniProt: Q13901