TMEFF1 Protein (AA 40-330) (His tag)

Produktnummer ABIN5852926

Produktdetails

Target: TMEFF1 (Transmembrane Protein with EGF-Like and Two Follistatin-Like Domains 1 (TMEFF1))

Protein-Typ: Recombinant

Proteineigenschaft: AA 40-330

Spezies: Human

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses TMEFF1 Protein ist gelabelt mit His tag.

Applikation: SDS-PAGE (SDS)

Sequenz: MGSSHHHHHH SSGLVPRGSH MGSSNQPPGG GGGSGGDCPG GKGKSINCSE LNVRESDVRV CDESSCKYGG VCKEDGDGLK CACQFQCHTN YIPVCGSNGD TYQNECFLRR AACKHQKEIT VIARGPCYSD NGSGSGEGEE EGSGAEVHRK HSKCGPCKYK AECDEDAENV GCVCNIDCSG YSFNPVCASD GSSYNNPCFV REASCIKQEQ IDIRHLGHCT DTDDTSLLGK KDDGLQYRPD VKDASDQRED VYIGNHMPCP ENLNGYCIHG KCEFIYSTQK ASCRCESGYT GQHCEKTDFS ILYVVPSRQK LTHV

Reinheit: > 90 % by SDS - PAGE

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.25 mg/mL

Buffer: Liquid. In 20  mM Tris-HCl buffer (  pH 8.0) containing 0.1M NaCl, 10 % glycerol.

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.

Antigendetails

Target: TMEFF1 (Transmembrane Protein with EGF-Like and Two Follistatin-Like Domains 1 (TMEFF1))

Andere Bezeichnung: TMEFF1 (TMEFF1 Produkte)

Synonyme: A830033E11 Protein, M7365 Protein, Tr1 Protein, C9orf2 Protein, CT120.1 Protein, H7365 Protein, TR-1 Protein, tomoregulin-1 Protein, fb53c10 Protein, tmeff1 Protein, wu:fb53c10 Protein, zgc:110069 Protein, transmembrane protein with EGF-like and two follistatin-like domains 1 Protein, transmembrane protein with EGF like and two follistatin like domains 1 Protein, myb/SANT-like DNA-binding domain-containing protein 3 Protein, transmembrane protein with EGF like and two follistatin like domains 1 S homeolog Protein, transmembrane protein with EGF-like and two follistatin-like domains 1b Protein, Tmeff1 Protein, TMEFF1 Protein, LOC612942 Protein, tmeff1.S Protein, tmeff1b Protein

Hintergrund: TMEFF1, also known as tomoregulin-1, is a type I transmembrane glycoprotein. This protein contains two follistatin modules and an EGF domain in its extracellular domain, a transmembrane domain and a short cytoplasmic tail. The extracellular domain of TMEFF1 can be released as a soluble protein. TMEFF1 is predominantly expressed in brain, but is downregulated in brain neoplasms. TMEFF1 selectively regulates nodal but not activin signaling through direct binding to the nodal co-receptor, Cripto. Recombinant human TMEFF1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Molekulargewicht: 33.9 kDa (314aa) confirmed by MALDI-TOF

NCBI Accession: NP_003683

UniProt: Q8IYR6