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METRNL Protein (AA 46-311) (His tag)

METRNL Spezies: Human Wirt: Hefe Recombinant > 90 % SDS
Produktnummer ABIN5714378
  • Target Alle METRNL Proteine anzeigen
    METRNL (Meteorin, Glial Cell Differentiation Regulator-Like (METRNL))
    Protein-Typ
    Recombinant
    Proteineigenschaft
    AA 46-311
    Spezies
    • 3
    • 2
    • 1
    • 1
    • 1
    Human
    Quelle
    • 3
    • 2
    • 2
    • 1
    Hefe
    Aufreinigungstag / Konjugat
    Dieses METRNL Protein ist gelabelt mit His tag.
    Applikation
    SDS-PAGE (SDS)
    Sequenz
    QYSSDRCSWK GSGLTHEAHR KEVEQVYLRC AAGAVEWMYP TGALIVNLRP NTFSPARHLT VCIRSFTDSS GANIYLEKTG ELRLLVPDGD GRPGRVQCFG LEQGGLFVEA TPQQDIGRRT TGFQYELVRR HRASDLHELS APCRPCSDTE VLLAVCTSDF AVRGSIQQVT HEPERQDSAI HLRVSRLYRQ KSRVFEPVPE GDGHWQGRVR TLLECGVRPG HGDFLFTGHM HFGEARLGCA PRFKDFQRMY RDAQERGLNP CEVGTD
    Aufreinigung
    SDS-PAGE
    Reinheit
    > 90 %
    Top Product
    Discover our top product METRNL Protein
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    0.1-2 mg/mL
    Buffer
    20 mM Tris-HCl based buffer, pH 8.0
    Lagerung
    -80 °C,4 °C,-20 °C
    Informationen zur Lagerung
    Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Target
    METRNL (Meteorin, Glial Cell Differentiation Regulator-Like (METRNL))
    Andere Bezeichnung
    METRL (METRNL Produkte)
    Synonyme
    9430048M07Rik Protein, BC019776 Protein, fc90a08 Protein, fj23b04 Protein, wu:fc90a08 Protein, wu:fj23b04 Protein, zgc:56225 Protein, meteorin like, glial cell differentiation regulator Protein, meteorin, glial cell differentiation regulator-like Protein, meteorin-like, glial cell differentiation regulator Protein, meteorin, glial cell differentiation regulator-like L homeolog Protein, METRNL Protein, Metrnl Protein, metrnl.L Protein, metrnl Protein
    Hintergrund
    Hormone induced following exercise or cold exposure that promotes energy expenditure. Induced either in the skeletal muscle after exercise or in adipose tissue following cold exposure and is present in the circulation. Able to stimulate energy expenditure associated with the browning of the white fat depots and improves glucose tolerance. Does not promote an increase in a thermogenic gene program via direct action on adipocytes, but acts by stimulating several immune cell subtypes to enter the adipose tissue and activate their prothermogenic actions. Stimulates an eosinophil-dependent increase in IL4 expression and promotes alternative activation of adipose tissue macrophages, which are required for the increased expression of the thermogenic and anti-inflammatory gene programs in fat. Required for some cold-induced thermogenic responses, suggesting a role in metabolic adaptations to cold tperatures .
    Molekulargewicht
    31.96 kDa
    UniProt
    Q641Q3
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