PAP Associated Domain Containing 7 (PAPD7) (AA 723-1012), (partial) protein (His tag)

Produktnummer ABIN4975135

Produktdetails

Target: PAP Associated Domain Containing 7 (PAPD7)

Protein-Typ: Recombinant

Proteineigenschaft: AA 723-1012, partial

Spezies: Infectious Bursal Disease Virus (IBDV)

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: His tag

Applikation: SDS-PAGE (SDS)

Sequenz: RFPHNPRDWD RLPYLNLPYL PPNAGRQYHL AMAASEFKET PELESAVRAM EAAANVDPLF QSALSVFMWL EENGIVTDMA NFALSDPNAH RMRNFLANAP QAGSKSQRAK YGTAGYGVEA RGPTPEEAQR EKDTRISKKM ETMGIYFATP EWVALNGHRG PSPGQLKYWQ NTREIPDPNE DYLDYVHAEK SRLASEEQIL RAATSIYGAP GQAEPPQAFI DEVAKVYEIN HGRGPNQEQM KDLLLTAMEM KHRNPRRALP KPKPKPNAPT QRPPGRLGRW IRTVSDEDLE

Aufreinigung: SDS-PAGE

Reinheit: > 90 %

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.1-2 mg/mL

Buffer: 20 mM Tris-HCl based buffer, pH 8.0

Lagerung: -80 °C,4 °C,-20 °C

Informationen zur Lagerung: Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

Antigendetails

Target: PAP Associated Domain Containing 7 (PAPD7)

Andere Bezeichnung: POLS (PAPD7 Produkte)

Synonyme: LAK-1 Protein, LAK1 Protein, POLK Protein, POLS Protein, TRF4 Protein, TRF4-1 Protein, TRF41 Protein, TUTASE5 Protein, TRF4-1b Protein, pols Protein, Pols Protein, DNA polymerase sigma Protein, poly(A) RNA polymerase D7, non-canonical Protein, non-canonical poly(A) RNA polymerase PAPD7 Protein, PAP associated domain containing 7 Protein, Eint_061490 Protein, PAPD7 Protein, LOC100579823 Protein, papd7 Protein, Papd7 Protein

Substanzklasse: Viral Protein

Hintergrund: Capsid protein VP2 self assbles to form an icosahedral capsid with a T=13 symmetry, about 70 nm in diameter, and consisting of 260 VP2 trimers. The capsid encapsulates the genomic dsRNA. VP2 is also involved in attachment and entry into the host cell by interacting with host ITGA4/ITGB1 .The precursor of VP2 plays an important role in capsid assbly. First, pre-VP2 and VP2 oligomers assble to form a procapsid. Then, the pre-VP2 intermediates may be processed into VP2 proteins by proteolytic cleavage mediated by VP4 to obtain the mature virion. The final capsid is composed of pentamers and hexamers but VP2 has a natural tendency to assble into all-pentameric structures. Therefore pre-VP2 may be required to allow formation of the hexameric structures .Protease VP4 is a serine protease that cleaves the polyprotein into its final products. Pre-VP2 is first partially cleaved, and may be completely processed by VP4 upon capsid maturation..

Molekulargewicht: 36.9 kDa

UniProt: P15480