Histone H2B Type 1-C/E/F/G/I (LOC100407767) (AA 2-125) protein (GST tag)

Produktnummer ABIN5712177

Produktdetails

Target: Histone H2B Type 1-C/E/F/G/I (LOC100407767)

Protein-Typ: Recombinant

Proteineigenschaft: AA 2-125

Spezies: Human

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: GST tag

Applikation: SDS-PAGE (SDS)

Sequenz: PEPAKSAPAP KKGSKKAVTK AQKKDGKKRK RSRKESYSVY VYKVLKQVHP DTGISSKAMG IMNSFVNDIF ERIAGEASRL AHYNKRSTIT SREIQTAVRL LLPGELAKHA VSEGTKAVTK YTSS

Aufreinigung: SDS-PAGE

Reinheit: > 90 %

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.1-2 mg/mL

Buffer: 20 mM Tris-HCl based buffer, pH 8.0

Lagerung: -80 °C,4 °C,-20 °C

Informationen zur Lagerung: Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

Antigendetails

Target: Histone H2B Type 1-C/E/F/G/I (LOC100407767)

Andere Bezeichnung: H2B1C (LOC100407767 Produkte)

Synonyme: H2B.1 Protein, H2B/l Protein, H2BFL Protein, dJ221C16.3 Protein, histone cluster 1 H2B family member c Protein, HIST1H2BC Protein

Hintergrund: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a tplate. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome rodeling.Has broad antibacterial activity. May contribute to the formation of the functional antimicrobial barrier of the colonic epithelium, and to the bactericidal activity of amniotic fluid.

Molekulargewicht: 41 kDa

UniProt: P62807