ARL2 Protein (AA 19-184, partial) (GST tag)

Produktnummer ABIN5712127

Produktdetails

Target: ARL2 (ADP-Ribosylation Factor-Like 2 (ARL2))

Protein-Typ: Recombinant

Proteineigenschaft: AA 19-184, partial

Spezies: Human

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses ARL2 Protein ist gelabelt mit GST tag.

Applikation: SDS-PAGE (SDS)

Sequenz: LLMLGLDNAG KTTILKKFNG EDIDTISPTL GFNIKTLEHR GFKLNIWDVG GQKSLRSYWR NYFESTDGLI WVVDSADRQR MQDCQRELQS LLVEERLAGA TLLIFANKQD LPGALSSNAI REVLELDSIR SHHWCIQGCS AVTGENLLPG IDWLLDDISS RIFTAD

Aufreinigung: SDS-PAGE

Reinheit: > 90 %

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.1-2 mg/mL

Buffer: 20 mM Tris-HCl based buffer, pH 8.0

Lagerung: -80 °C,4 °C,-20 °C

Informationen zur Lagerung: Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

Antigendetails

Target: ARL2 (ADP-Ribosylation Factor-Like 2 (ARL2))

Andere Bezeichnung: ARL2 (ARL2 Produkte)

Synonyme: arfl2 Protein, MGC75676 Protein, ARFL2 Protein, 2610009M23Rik Protein, AI115441 Protein, AW553335 Protein, ADP ribosylation factor like GTPase 2 Protein, ADP-ribosylation factor-like 2 Protein, ADP-ribosylation factor like GTPase 2 Protein, arl2 Protein, ARL2 Protein, Arl2 Protein

Hintergrund: Small GTP-binding protein which cycles between an inactive GDP-bound and an active GTP-bound form, and the rate of cycling is regulated by guanine nucleotide exchange factors (GEF) and GTPase-activating proteins (GAP). GTP-binding protein that does not act as an allosteric activator of the cholera toxin catalytic subunit. Regulates formation of new microtubules and centrosome integrity. Prevents the TBCD-induced microtubule destruction. Participates in association with TBCD, in the disassbly of the apical junction complexes. Antagonizes the effect of TBCD on epithelial cell detachment and tight and adherens junctions disassbly. Together with ARL2, plays a role in the nuclear translocation, retention and transcriptional activity of STAT3. Component of a regulated secretory pathway involved in Ca2+-dependent release of acetylcholine. Required for normal progress through the cell cycle.

Molekulargewicht: 46.1 kDa

UniProt: P36404

Pathways: Cell-Cell Junction Organization, Maintenance of Protein Location