EIF4A2 Protein (AA 1-407, full length) (GST tag)

Produktnummer ABIN5712053

Produktdetails

Target: EIF4A2 (Eukaryotic Translation Initiation Factor 4A2 (EIF4A2))

Protein-Typ: Recombinant

Proteineigenschaft: full length, AA 1-407

Spezies: Human

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses EIF4A2 Protein ist gelabelt mit GST tag.

Applikation: SDS-PAGE (SDS)

Sequenz: MSGGSADYNR EHGGPEGMDP DGVIESNWNE IVDNFDDMNL KESLLRGIYA YGFEKPSAIQ QRAIIPCIKG YDVIAQAQSG TGKTATFAIS ILQQLEIEFK ETQALVLAPT RELAQQIQKV ILALGDYMGA TCHACIGGTN VRNEMQKLQA EAPHIVVGTP GRVFDMLNRR YLSPKWIKMF VLDEADEMLS RGFKDQIYEI FQKLNTSIQV VLLSATMPTD VLEVTKKFMR DPIRILVKKE ELTLEGIKQF YINVEREEWK LDTLCDLYET LTITQAVIFL NTRRKVDWLT EKMHARDFTV SALHGDMDQK ERDVIMREFR SGSSRVLITT DLLARGIDVQ QVSLVINYDL PTNRENYIHR IGRGGRFGRK GVAINFVTEE DKRILRDIET FYNTTVEEMP MNVADLI

Aufreinigung: SDS-PAGE

Reinheit: > 90 %

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.1-2 mg/mL

Buffer: 20 mM Tris-HCl based buffer, pH 8.0

Lagerung: -80 °C,4 °C,-20 °C

Informationen zur Lagerung: Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

Antigendetails

Target: EIF4A2 (Eukaryotic Translation Initiation Factor 4A2 (EIF4A2))

Andere Bezeichnung: IF4A2 (EIF4A2 Produkte)

Synonyme: BM-010 Protein, DDX2B Protein, EIF4A Protein, EIF4F Protein, eIF-4A-II Protein, eIF4A-II Protein, 4833432N07Rik Protein, Ddx2b Protein, Eif4 Protein, ddx2b Protein, eif4aii Protein, eif4f Protein, xeif4aii Protein, EIF4A2 Protein, EIF4AII Protein, wu:fd50g11 Protein, zgc:63783 Protein, eukaryotic translation initiation factor 4A2 Protein, eukaryotic translation initiation factor 4A2 L homeolog Protein, microRNA 1248 Protein, eukaryotic translation initiation factor 4A, isoform 2 Protein, Eif4a2 Protein, EIF4A2 Protein, eif4a2.L Protein, eif4a2 Protein, MIR1248 Protein

Hintergrund: ATP-dependent RNA helicase which is a subunit of the eIF4F complex involved in cap recognition and is required for mRNA binding to ribosome. In the current model of translation initiation, eIF4A unwinds RNA secondary structures in the 5'-UTR of mRNAs which is necessary to allow efficient binding of the small ribosomal subunit, and subsequent scanning for the initiator codon.

Molekulargewicht: 73.8 kDa

UniProt: Q14240