TEAD3 Protein (AA 112-435, partial) (His-SUMO Tag)

Produktnummer ABIN5711743

Produktdetails

Target: TEAD3 (TEA Domain Family Member 3 (TEAD3))

Protein-Typ: Recombinant

Proteineigenschaft: AA 112-435, partial

Spezies: Human

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses TEAD3 Protein ist gelabelt mit His-SUMO Tag.

Applikation: SDS-PAGE (SDS)

Sequenz: MNLDQVSKDK ALQSMASMSS AQIVSASVLQ NKFSPPSPLP QAVFSTSSRF WSSPPLLGQQ PGPSQDIKPF AQPAYPIQPP LPPTLSSYEP LAPLPSAAAS VPVWQDRTIA SSRLRLLEYS AFMEVQRDPD TYSKHLFVHI GQTNPAFSDP PLEAVDVRQI YDKFPEKKGG LKELYEKGPP NAFFLVKFWA DLNSTIQEGP GAFYGVSSQY SSADSMTISV STKVCSFGKQ VVEKVETEYA RLENGRFVYR IHRSPMCEYM INFIHKLKHL PEKYMMNSVL ENFTILQVVT SRDSQETLLV IAFVFEVSTS EHGAQHHVYK LVKD

Aufreinigung: SDS-PAGE

Reinheit: > 90 %

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.1-2 mg/mL

Buffer: 20 mM Tris-HCl based buffer, pH 8.0

Lagerung: -80 °C,4 °C,-20 °C

Informationen zur Lagerung: Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

Antigendetails

Target: TEAD3 (TEA Domain Family Member 3 (TEAD3))

Andere Bezeichnung: TEAD3 (TEAD3 Produkte)

Synonyme: DTEF-1 Protein, TEF-5 Protein, ETFR-1 Protein, TEAD-3 Protein, TEAD5 Protein, TEF5 Protein, Tcf13r2 Protein, cb882 Protein, tead3 Protein, TEA domain transcription factor 3 Protein, TEA domain family member 3 Protein, TEA domain family member 3 a Protein, tubby like protein 1 Protein, TEAD3 Protein, Tead3 Protein, tead3a Protein, TULP1 Protein

Hintergrund: Transcription factor which plays a key role in the Hippo signaling pathway, a pathway involved in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein MST1/MST2, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ. Acts by mediating gene expression of YAP1 and WWTR1/TAZ, thereby regulating cell proliferation, migration and epithelial mesenchymal transition (T) induction. Binds to multiple functional elents of the human chorionic somatomammotropin-B gene enhancer.

Molekulargewicht: 52.3 kDa

UniProt: Q99594

Pathways: Regulation of Lipid Metabolism by PPARalpha