RBBP7 Protein (AA 1-425, full length) (His-SUMO Tag)

Produktnummer ABIN5711301

Produktdetails

Target: RBBP7 (Retinoblastoma Binding Protein 7 (RBBP7))

Protein-Typ: Recombinant

Proteineigenschaft: full length, AA 1-425

Spezies: Human

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses RBBP7 Protein ist gelabelt mit His-SUMO Tag.

Applikation: SDS-PAGE (SDS)

Sequenz: MASKEMFEDT VEERVINEEY KIWKKNTPFL YDLVMTHALQ WPSLTVQWLP EVTKPEGKDY ALHWLVLGTH TSDEQNHLVV ARVHIPNDDA QFDASHCDSD KGEFGGFGSV TGKIECEIKI NHEGEVNRAR YMPQNPHIIA TKTPSSDVLV FDYTKHPAKP DPSGECNPDL RLRGHQKEGY GLSWNSNLSG HLLSASDDHT VCLWDINAGP KEGKIVDAKA IFTGHSAVVE DVAWHLLHES LFGSVADDQK LMIWDTRSNT TSKPSHLVDA HTAEVNCLSF NPYSEFILAT GSADKTVALW DLRNLKLKLH TFESHKDEIF QVHWSPHNET ILASSGTDRR LNVWDLSKIG EEQSAEDAED GPPELLFIHG GHTAKISDFS WNPNEPWVIC SVSEDNIMQI WQMAENIYND EESDVTTSEL EGQGS

Aufreinigung: SDS-PAGE

Reinheit: > 90 %

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.1-2 mg/mL

Buffer: 20 mM Tris-HCl based buffer, pH 8.0

Lagerung: -80 °C,4 °C,-20 °C

Informationen zur Lagerung: Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

Antigendetails

Target: RBBP7 (Retinoblastoma Binding Protein 7 (RBBP7))

Andere Bezeichnung: RBBP7 (RBBP7 Produkte)

Synonyme: RbAp46 Protein, AA409861 Protein, AI173248 Protein, AU019541 Protein, BB114024 Protein, mRbAp46 Protein, rbap46 Protein, RBBP7 Protein, RBBP-7 Protein, Caf1 Protein, rbbp7 Protein, wu:fa13g08 Protein, wu:fb50h10 Protein, wu:fc29d09 Protein, zgc:56477 Protein, zgc:85617 Protein, CaO19.2146 Protein, RB binding protein 7, chromatin remodeling factor Protein, retinoblastoma binding protein 7, chromatin remodeling factor Protein, retinoblastoma binding protein 7 L homeolog Protein, retinoblastoma binding protein 7 Protein, retinoblastoma binding protein 4, like Protein, histone-binding protein RBBP7 Protein, Hat2p Protein, RBBP7 Protein, Rbbp7 Protein, rbbp7.L Protein, rbbp7 Protein, rbb4l Protein, LOC108708306 Protein, HAT2 Protein

Hintergrund: Core histone-binding subunit that may target chromatin rodeling factors, histone acetyltransferases and histone deacetylases to their histone substrates in a manner that is regulated by nucleosomal DNA. Component of several complexes which regulate chromatin metabolism. These include the type B histone acetyltransferase (HAT) complex, which is required for chromatin assbly following DNA replication, the core histone deacetylase (HDAC) complex, which promotes histone deacetylation and consequent transcriptional repression, the nucleosome rodeling and histone deacetylase complex (the NuRD complex), which promotes transcriptional repression by histone deacetylation and nucleosome rodeling, and the PRC2/EED-EZH2 complex, which promotes repression of homeotic genes during development, and the NURF (nucleosome rodeling factor) complex.

Molekulargewicht: 63.8 kDa

UniProt: Q16576