PHOSP (AA 1-297), (full length) protein (His tag)
Spezies: Rabies Virus
Wirt: Escherichia coli (E. coli)
Recombinant
> 90 %
SDS
1 image
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- Target
- PHOSP
- Protein-Typ
- Recombinant
- Proteineigenschaft
- full length, AA 1-297
- Spezies
- Rabies Virus
- Quelle
- Escherichia coli (E. coli)
- Aufreinigungstag / Konjugat
- His tag
- Applikation
- SDS-PAGE (SDS)
- Sequenz
- MSKIFVNPSA IRAGLADLEM AEETVDLINR NIEDNQAHLQ GEPIEVDNLP EDMGRLHLDD GKSPNPGEMA KVGEGKYRED FQMDEGEDPS FLFQSYLENV GVQIVRQMRS GERFLKIWSQ TVEEIISYVA VNFPNPPGKS SEDKSTQTTG RELKKETTPT PSQRESQSSK ARMAAQTASG PPALEWSATN EKDDLSVEAE IAHQIAESFS KKYKFPSRSS GILLYNFEQL KMNLDDIVKE AKNVPGVTRL AHDGSKLPLR CVLGWVALAN SKKFQLLVES DKLSKIMQDD LNRYTSC
- Aufreinigung
- SDS-PAGE
- Reinheit
- > 90 %
-
- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Format
- Liquid
- Konzentration
- 0.1-2 mg/mL
- Buffer
- 20 mM Tris-HCl based buffer, pH 8.0
- Lagerung
- -80 °C,4 °C,-20 °C
- Informationen zur Lagerung
- Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
-
- Target
- PHOSP
- Substanzklasse
- Viral Protein
- Hintergrund
- Non catalytic polymerase cofactor and regulatory protein that plays a role in viral transcription and replication. Stabilizes the RNA polymerase L to the N-RNA tplate and binds the soluble protein N, preventing it from encapsidating non-genomic RNA. Also inhibits host IFN-alpha and IFN-beta signaling by binding and retaining phosphorylated STAT1 in the cytoplasm or by inhibiting the DNA binding of STAT1 in the nucleus. Might be involved, through interaction with host dynein, in intracellular microtubule-dependent virus transport of incoming virus from the synapse toward the cell body .
- Molekulargewicht
- 37.3 kDa
- UniProt
- P69480
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