QPCT Protein (AA 29-361) (His-SUMO Tag)

Produktnummer ABIN4976140

Produktdetails

Target: QPCT (Glutaminyl-Peptide Cyclotransferase (QPCT))

Protein-Typ: Recombinant

Proteineigenschaft: AA 29-361

Spezies: Human

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses QPCT Protein ist gelabelt mit His-SUMO Tag.

Applikation: SDS-PAGE (SDS)

Sequenz: VSPSASAWPE EKNYHQPAIL NSSALRQIAE GTSISEMWQN DLQPLLIERY PGSPGSYAAR QHIMQRIQRL QADWVLEIDT FLSQTPYGYR SFSNIISTLN PTAKRHLVLA CHYDSKYFSH WNNRVFVGAT DSAVPCAMML ELARALDKKL LSLKTVSDSK PDLSLQLIFF DGEEAFLHWS PQDSLYGSRH LAAKMASTPH PPGARGTSQL HGMDLLVLLD LIGAPNPTFP NFFPNSARWF ERLQAIEHEL HELGLLKDHS LEGRYFQNYS YGGVIQDDHI PFLRRGVPVL HLIPSPFPEV WHTMDDNEEN LDESTIDNLN KILQVFVLEY LHL

Aufreinigung: SDS-PAGE

Reinheit: > 90 %

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.1-2 mg/mL

Buffer: 20 mM Tris-HCl based buffer, pH 8.0

Lagerung: -80 °C,4 °C,-20 °C

Informationen zur Lagerung: Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

Antigendetails

Target: QPCT (Glutaminyl-Peptide Cyclotransferase (QPCT))

Andere Bezeichnung: QPCT (QPCT Produkte)

Synonyme: GCT Protein, QC Protein, sQC Protein, QPCT Protein, 5730422A13Rik Protein, Qpctl1 Protein, RGD1562284 Protein, qpct Protein, glutaminyl-peptide cyclotransferase Protein, glutaminyl-peptide cyclotransferase (glutaminyl cyclase) Protein, glutaminyl-peptide cyclotransferase L homeolog Protein, QPCT Protein, Qpct Protein, M6_Spy0443 Protein, M5005_Spy_0416 Protein, M28_Spy0404 Protein, CJA_2408 Protein, CCNA_02733 Protein, Tsp_03182 Protein, qpct.L Protein

Hintergrund: Responsible for the biosynthesis of pyroglutamyl peptides. Has a bias against acidic and tryptophan residues adjacent to the N-terminal glutaminyl residue and a lack of importance of chain length after the second residue. Also catalyzes N-terminal pyroglutamate formation. In vitro, catalyzes pyroglutamate formation of N-terminally truncated form of APP amyloid-beta peptides [Glu-3]-beta-amyloid. May be involved in the N-terminal pyroglutamate formation of several amyloid-related plaque-forming peptides.

Molekulargewicht: 53.9 kDa

UniProt: Q16769