ORC4 Protein (AA 1-436, full length) (His-SUMO Tag)

Produktnummer ABIN5710049

Produktdetails

Target: ORC4 (Origin Recognition Complex, Subunit 4 (ORC4))

Protein-Typ: Recombinant

Proteineigenschaft: full length, AA 1-436

Spezies: Human

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses ORC4 Protein ist gelabelt mit His-SUMO Tag.

Applikation: SDS-PAGE (SDS)

Sequenz: MSSRKSKSNS LIHTECLSQV QRILRERFCR QSPHSNLFGV QVQYKHLSEL LKRTALHGES NSVLIIGPRG SGKTMLINHA LKELMEIEEV SENVLQVHLN GLLQINDKIA LKEITRQLNL ENVVGDKVFG SFAENLSFLL EALKKGDRTS SCPVIFILDE FDLFAHHKNQ TLLYNLFDIS QSAQTPIAVI GLTCRLDILE LLEKRVKSRF SHRQIHLMNS FGFPQYVKIF KEQLSLPAEF PDKVFAEKWN ENVQYLSEDR SVQEVLQKHF NISKNLRSLH MLLMLALNRV TASHPFMTAV DLMEASQLCS MDSKANIVHG LSVLEICLII AMKHLNDIYE EEPFNFQMVY NEFQKFVQRK AHSVYNFEKP VVMKAFEHLQ QLELIKPMER TSGNSQREYQ LMKLLLDNTQ IMNALQKYPN CPTDVRQWAT SSLSWL

Aufreinigung: SDS-PAGE

Reinheit: > 90 %

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.1-2 mg/mL

Buffer: 20 mM Tris-HCl based buffer, pH 8.0

Lagerung: -80 °C,4 °C,-20 °C

Informationen zur Lagerung: Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

Antigendetails

Target: ORC4 (Origin Recognition Complex, Subunit 4 (ORC4))

Andere Bezeichnung: ORC4 (ORC4 Produkte)

Synonyme: ORC4L Protein, ORC4P Protein, Orc4P Protein, Orc4l Protein, mMmORC4 Protein, CG2917 Protein, DmORC4 Protein, Dmel\\CG2917 Protein, ORC Protein, ORC4 Protein, dmOrc4 Protein, orc4 Protein, rDmORC Protein, orc4l Protein, fc50c03 Protein, wu:fc50c03 Protein, zgc:85772 Protein, ATORC4 Protein, F23H14.9 Protein, F23H14_9 Protein, ORIGIN RECOGNITION COMPLEX SUBUNIT 4 Protein, origin recognition complex subunit 4 Protein, origin recognition complex subunit 4 Protein, origin recognition complex, subunit 4 Protein, Origin recognition complex subunit 4 Protein, origin recognition complex subunit 4 L homeolog Protein, origin recognition complex subunit Orc4 Protein, ORC4 Protein, Orc4 Protein, orc4.L Protein, orc4 Protein, CNM01830 Protein

Hintergrund: Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent. The specific DNA sequences that define origins of replication have not been identified yet. ORC is required to assble the pre-replication complex necessary to initiate DNA replication. Binds histone H3 and H4 trimethylation marks H3K9me3, H3K27me3 and H4K20me3.

Molekulargewicht: 66.3 kDa

UniProt: O43929

Pathways: Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA