NUP153 Protein (AA 657-880) (His tag)

Produktnummer ABIN5710031

Produktdetails

Target: NUP153 (Nucleoporin 153kDa (NUP153))

Protein-Typ: Recombinant

Proteineigenschaft: AA 657-880

Spezies: Human

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses NUP153 Protein ist gelabelt mit His tag.

Applikation: SDS-PAGE (SDS)

Sequenz: KAGSSWQCDT CLLQNKVTDN KCIACQAAKL SPRDTAKQTG IETPNKSGKT TLSASGTGFG DKFKPVIGTW DCDTCLVQNK PEAIKCVACE TPKPGTCVKR ALTLTVVSES AETMTASSSS CTVTTGTLGF GDKFKRPIGS WECSVCCVSN NAEDNKCVSC MSEKPGSSVP ASSSSTVPVS LPSGGSLGLE KFKKPEGSWD CELCLVQNKA DSTKCLACES AKPG

Aufreinigung: SDS-PAGE

Reinheit: > 90 %

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.1-2 mg/mL

Buffer: 20 mM Tris-HCl based buffer, pH 8.0

Lagerung: -80 °C,4 °C,-20 °C

Informationen zur Lagerung: Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

Antigendetails

Target: NUP153 (Nucleoporin 153kDa (NUP153))

Andere Bezeichnung: NU153 (NUP153 Produkte)

Synonyme: CG4453 Protein, Dmel\\CG4453 Protein, NUP153 Protein, Nup 153 Protein, dNup153 Protein, dmNup153 Protein, nup153 Protein, NUCZINK Protein, B130015D15Rik Protein, C88147 Protein, HNUP153 Protein, N153 Protein, Nucleoporin 153kD Protein, nucleoporin 153 Protein, nucleoporin 153kDa L homeolog Protein, Nup153 Protein, NUP153 Protein, nup153.L Protein

Hintergrund: Component of the nuclear pore complex (NPC), a complex required for the trafficking across the nuclear envelope. Functions as a scaffolding elent in the nuclear phase of the NPC essential for normal nucleocytoplasmic transport of proteins and mRNAs. Involved in the quality control and retention of unspliced mRNAs in the nucleus, in association with TPR, regulates the nuclear export of unspliced mRNA species bearing constitutive transport elent (CTE) in a NXF1- and KHDRBS1-independent manner. Mediates TPR anchoring to the nuclear mbrane at NPC. The repeat-containing domain may be involved in anchoring other components of the NPC to the pore mbrane. Possible DNA-binding subunit of the nuclear pore complex (NPC).

Molekulargewicht: 27.4 kDa

UniProt: P49790

Pathways: Protein targeting to Nucleus