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NDST1 Protein (AA 40-556, Isoform 2) (His-SUMO Tag)

NDST1 Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant > 90 % SDS
Produktnummer ABIN5709995
  • Target Alle NDST1 Proteine anzeigen
    NDST1 (N-Deacetylase/N-Sulfotransferase (Heparan Glucosaminyl) 1 (NDST1))
    Protein-Typ
    Recombinant
    Proteineigenschaft
    AA 40-556, Isoform 2
    Spezies
    • 5
    • 2
    Human
    Quelle
    • 2
    • 2
    • 2
    • 1
    Escherichia coli (E. coli)
    Aufreinigungstag / Konjugat
    Dieses NDST1 Protein ist gelabelt mit His-SUMO Tag.
    Applikation
    SDS-PAGE (SDS)
    Sequenz
    GWKRGLEPSA DAPEPDCGDP PPVAPSRLLP LKPVQAATPS RTDPLVLVFV ESLYSQLGQE VVAILESSRF KYRTEIAPGK GDMPTLTDKG RGRFALIIYE NILKYVNLDA WNRELLDKYC VAYGVGIIGF FKANENSLLS AQLKGFPLFL HSNLGLKDCS INPKSPLLYV TRPSEVEKGV LPGEDWTVFQ SNHSTYEPVL LAKTRSSESI PHLGADAGLH AALHATVVQD LGLHDGIQRV LFGNNLNFWL HKLVFVDAVA FLTGKRLSLP LDRYILVDID DIFVGKEGTR MKVEDVKALF DTQNELRAHI PNFTFNLGYS GKFFQTGTNA EDAGDDLLLS YVKEFWWFPH MWSHMQPHLF HNQSVLAEQM ALNKKFAVEH GIPTDMGYAV APHHSGVYPV HVQLYEAWKQ VWSIRVTSTE EYPHLKPARY RRGFIHNGIM VLPRQTCGLF THTIFYNEYP GGSSELDKII NGGELFLTVL LNPVSAPQPM AAGEKGLLHS LSAADTGFLE PGKGGEA
    Aufreinigung
    SDS-PAGE
    Reinheit
    > 90 %
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  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    0.1-2 mg/mL
    Buffer
    20 mM Tris-HCl based buffer, pH 8.0
    Lagerung
    -80 °C,4 °C,-20 °C
    Informationen zur Lagerung
    Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Target
    NDST1 (N-Deacetylase/N-Sulfotransferase (Heparan Glucosaminyl) 1 (NDST1))
    Andere Bezeichnung
    NDST1 (NDST1 Produkte)
    Synonyme
    HSST Protein, NST1 Protein, 1200015G06Rik Protein, Hsst Protein, NDST-1 Protein, fj47c03 Protein, ndst1 Protein, wu:fj47c03 Protein, NDST1 Protein, N-deacetylase and N-sulfotransferase 1 Protein, N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1 Protein, N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1b Protein, N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1 S homeolog Protein, NDST1 Protein, Ndst1 Protein, ndst1b Protein, ndst1 Protein, ndst1.S Protein
    Hintergrund
    Essential bifunctional enzyme that catalyzes both the N-deacetylation and the N-sulfation of glucosamine (GlcNAc) of the glycosaminoglycan in heparan sulfate. Modifies the GlcNAc-GlcA disaccharide repeating sugar backbone to make N-sulfated heparosan, a prerequisite substrate for later modifications in heparin biosynthesis. Plays a role in determining the extent and pattern of sulfation of heparan sulfate. Compared to other NDST enzymes, its presence is absolutely required. Participates in biosynthesis of heparan sulfate that can ultimately serve as L-selectin ligands, thereby playing a role in inflammatory response.
    Molekulargewicht
    73.5 kDa
    UniProt
    P52848
    Pathways
    Regulation of Systemic Arterial Blood Pressure by Hormones, Glycosaminoglycan Metabolic Process
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