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NANOS2 Protein (AA 1-138, full length) (His-SUMO Tag)

NANOS2 Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant > 90 % SDS
Produktnummer ABIN5709987
  • Target Alle NANOS2 Proteine anzeigen
    NANOS2 (Nanos Homolog 2 (NANOS2))
    Protein-Typ
    Recombinant
    Proteineigenschaft
    AA 1-138, full length
    Spezies
    • 3
    • 1
    Human
    Quelle
    • 2
    • 1
    • 1
    Escherichia coli (E. coli)
    Aufreinigungstag / Konjugat
    Dieses NANOS2 Protein ist gelabelt mit His-SUMO Tag.
    Applikation
    SDS-PAGE (SDS)
    Sequenz
    MQLPPFDMWK DYFNLSQVVW ALIASRGQRL ETQEIEEPSP GPPLGQDQGL GAPGANGGLG TLCNFCKHNG ESRHVYSSHQ LKTPDGVVVC PILRHYVCPV CGATGDQAHT LKYCPLNGGQ QSLYRRSGRN SAGRRVKR
    Aufreinigung
    SDS-PAGE
    Reinheit
    > 90 %
    Top Product
    Discover our top product NANOS2 Protein
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    0.1-2 mg/mL
    Buffer
    20 mM Tris-HCl based buffer, pH 8.0
    Lagerung
    -80 °C,4 °C,-20 °C
    Informationen zur Lagerung
    Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Target
    NANOS2 (Nanos Homolog 2 (NANOS2))
    Andere Bezeichnung
    NANO2 (NANOS2 Produkte)
    Synonyme
    NOS2 Protein, RGD1562436 Protein, nos2 Protein, nanos C2HC-type zinc finger 2 Protein, nanos homolog 2 (Drosophila) Protein, nanos 2 Protein, nanos2 protein Protein, NANOS2 Protein, Nanos2 Protein, nanos2 Protein
    Hintergrund
    Plays a key role in the sexual differentiation of germ cells by promoting the male fate but suppressing the fale fate. Represses the fale fate pathways by suppressing meiosis, which in turn results in the promotion of the male fate. Maintains the suppression of meiosis by preventing STRA8 expression, which is required for preiotic DNA replication, after CYP26B1 is decreased. Regulates the localization of the CCR4-NOT deadenylation complex to P-bodies and plays a role in recruiting the complex to trigger the degradation of mRNAs involved in meiosis. Required for the maintenance of the spermatogonial st cell population. Not essential for the assbly of P-bodies but is required for the maintenance of their normal state .
    Molekulargewicht
    31.1 kDa
    UniProt
    P60321
    Pathways
    Retinoic Acid Receptor Signaling Pathway, Cellular Response to Molecule of Bacterial Origin, Stem Cell Maintenance
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