tau Protein (AA 2-459) (His-SUMO Tag)

Produktnummer ABIN5709911

Produktdetails

Target: tau (tau Protein)

Protein-Typ: Recombinant

Proteineigenschaft: AA 2-459

Spezies: Rhesusaffen

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses tau Protein ist gelabelt mit His-SUMO Tag.

Applikation: SDS-PAGE (SDS)

Sequenz: AEPRQEFDVM EDHAGTYGLG DRKDQEGYTM LQDQEGDTDA GLKESPLQTP AEDGSEELGS ETSDAKSTPT AEDVTAPLVD ERAPGEQAAA QPHMEIPEGT TAEEAGIGDT PSLEDEAAGH VTQARMVSKS KDGTGSDDKK AKGADGKTKI ATPRGAAPPG QKGQANATRI PAKTPPAPKT PPSSATKQVQ RKPPPAEPTS ERGEPPKSGD RSGYSSPGSP GTPGSRSRTP SLPTPPAREP KKVAVVRTPP KSPSSAKSRL QTAPVPMPDL KNVKSKIGST ENLKHQPGGG KVQIINKKLD LSNVQSKCGS KDNIKHVPGG GSVQIVYKPV DLSKVTSKCG SLGNIHHKPG GGQVEVKSEK LDFKDRVQSK IGSLDNITHV PGGGNKKIET HKLTFRENAK AKTDHGAEIV YKSPVVSGDT SPRHLSNVSS TGSIDMVDSP QLATLADEVS ASLAKQGL

Aufreinigung: SDS-PAGE

Reinheit: > 90 %

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.1-2 mg/mL

Buffer: 20 mM Tris-HCl based buffer, pH 8.0

Lagerung: -80 °C,4 °C,-20 °C

Informationen zur Lagerung: Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

Antigendetails

Target: tau (tau Protein)

Andere Bezeichnung: tau (tau Produkte)

Synonyme: DDPAC Protein, FTDP-17 Protein, MAPTL Protein, MSTD Protein, MTBT1 Protein, MTBT2 Protein, PPND Protein, TAU Protein, tau Protein, PHF-tau Protein, microtubule associated protein tau Protein, MAPT Protein

Hintergrund: Promotes microtubule assbly and stability, and might be involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubules while the N-terminus binds neural plasma mbrane components, suggesting that tau functions as a linker protein between both. Axonal polarity is predetermined by tau localization (in the neuronal cell) in the domain of the cell body defined by the centrosome. The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms may preferentially play a role in its stabilization.

Molekulargewicht: 63.8 kDa

UniProt: P57786