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Id2 Protein (AA 1-134, full length) (His-SUMO Tag)

Id2 Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant > 90 % SDS
Produktnummer ABIN5709695
  • Target Alle Id2 Proteine anzeigen
    Id2 (Inhibitor of DNA Binding 2 (Id2))
    Protein-Typ
    Recombinant
    Proteineigenschaft
    full length, AA 1-134
    Spezies
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Quelle
    • 6
    • 2
    • 2
    • 1
    Escherichia coli (E. coli)
    Aufreinigungstag / Konjugat
    Dieses Id2 Protein ist gelabelt mit His-SUMO Tag.
    Applikation
    SDS-PAGE (SDS)
    Sequenz
    MKAFSPVRSV RKNSLSDHSL GISRSKTPVD DPMSLLYNMN DCYSKLKELV PSIPQNKKVS KMEILQHVID YILDLQIALD SHPTIVSLHH QRPGQNQASR TPLTTLNTDI SILSLQASEF PSELMSNDSK ALCG
    Aufreinigung
    SDS-PAGE
    Reinheit
    > 90 %
    Top Product
    Discover our top product Id2 Protein
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    0.1-2 mg/mL
    Buffer
    20 mM Tris-HCl based buffer, pH 8.0
    Lagerung
    -80 °C,4 °C,-20 °C
    Informationen zur Lagerung
    Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Target
    Id2 (Inhibitor of DNA Binding 2 (Id2))
    Andere Bezeichnung
    ID2 (Id2 Produkte)
    Synonyme
    AI255428 Protein, C78922 Protein, Idb2 Protein, bHLHb26 Protein, Ac2-300 Protein, GIG8 Protein, ID2A Protein, ID2H Protein, XId2 Protein, id2-A Protein, inhibitor of DNA binding 2 Protein, inhibitor of DNA binding 2, HLH protein Protein, inhibitor of DNA binding 2 L homeolog Protein, Id2 Protein, ID2 Protein, id2.L Protein
    Hintergrund
    Transcriptional regulator (lacking a basic DNA binding domain) which negatively regulates the basic helix-loop-helix (bHLH) transcription factors by forming heterodimers and inhibiting their DNA binding and transcriptional activity. Implicated in regulating a variety of cellular processes, including cellular growth, senescence, differentiation, apoptosis, angiogenesis, and neoplastic transformation. Inhibits skeletal muscle and cardiac myocyte differentiation. Regulates the circadian clock by repressing the transcriptional activator activity of the CLOCK-ARNTL/BMAL1 heterodimer. Restricts the CLOCK and ARNTL/BMAL1 localization to the cytoplasm. Plays a role in both the input and output pathways of the circadian clock: in the input component, is involved in modulating the magnitude of photic entrainment and in the output component, contributes to the regulation of a variety of liver clock-controlled genes involved in lipid metabolism.
    Molekulargewicht
    30.9 kDa
    UniProt
    Q02363
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