Id2 Protein (AA 1-134, full length) (His-SUMO Tag)
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- Target Alle Id2 Proteine anzeigen
- Id2 (Inhibitor of DNA Binding 2 (Id2))
- Protein-Typ
- Recombinant
- Proteineigenschaft
- full length, AA 1-134
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Spezies
- Human
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Quelle
- Escherichia coli (E. coli)
- Aufreinigungstag / Konjugat
- Dieses Id2 Protein ist gelabelt mit His-SUMO Tag.
- Applikation
- SDS-PAGE (SDS)
- Sequenz
- MKAFSPVRSV RKNSLSDHSL GISRSKTPVD DPMSLLYNMN DCYSKLKELV PSIPQNKKVS KMEILQHVID YILDLQIALD SHPTIVSLHH QRPGQNQASR TPLTTLNTDI SILSLQASEF PSELMSNDSK ALCG
- Aufreinigung
- SDS-PAGE
- Reinheit
- > 90 %
- Top Product
- Discover our top product Id2 Protein
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- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 0.1-2 mg/mL
- Buffer
- 20 mM Tris-HCl based buffer, pH 8.0
- Lagerung
- -80 °C,4 °C,-20 °C
- Informationen zur Lagerung
- Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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- Target
- Id2 (Inhibitor of DNA Binding 2 (Id2))
- Andere Bezeichnung
- ID2 (Id2 Produkte)
- Synonyme
- AI255428 Protein, C78922 Protein, Idb2 Protein, bHLHb26 Protein, Ac2-300 Protein, GIG8 Protein, ID2A Protein, ID2H Protein, XId2 Protein, id2-A Protein, inhibitor of DNA binding 2 Protein, inhibitor of DNA binding 2, HLH protein Protein, inhibitor of DNA binding 2 L homeolog Protein, Id2 Protein, ID2 Protein, id2.L Protein
- Hintergrund
- Transcriptional regulator (lacking a basic DNA binding domain) which negatively regulates the basic helix-loop-helix (bHLH) transcription factors by forming heterodimers and inhibiting their DNA binding and transcriptional activity. Implicated in regulating a variety of cellular processes, including cellular growth, senescence, differentiation, apoptosis, angiogenesis, and neoplastic transformation. Inhibits skeletal muscle and cardiac myocyte differentiation. Regulates the circadian clock by repressing the transcriptional activator activity of the CLOCK-ARNTL/BMAL1 heterodimer. Restricts the CLOCK and ARNTL/BMAL1 localization to the cytoplasm. Plays a role in both the input and output pathways of the circadian clock: in the input component, is involved in modulating the magnitude of photic entrainment and in the output component, contributes to the regulation of a variety of liver clock-controlled genes involved in lipid metabolism.
- Molekulargewicht
- 30.9 kDa
- UniProt
- Q02363
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