HIST1H2BD Protein (AA 2-126) (His-SUMO Tag)

Produktnummer ABIN5709659

Produktdetails

Target: HIST1H2BD (Histone Cluster 1, H2bd (HIST1H2BD))

Protein-Typ: Recombinant

Proteineigenschaft: AA 2-126

Spezies: Human

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses HIST1H2BD Protein ist gelabelt mit His-SUMO Tag.

Applikation: SDS-PAGE (SDS)

Sequenz: PEPSKSAPAP KKGSKKAITK AQKKDGKKRK RSRKESYSIY VYKVLKQVHP DTGISSKAMG IMNSFVNDIF ERIAGEASRL AHYNKRSTIT SREIQTAVRL LLPGELAKHA VSEGTKAVTK YTSSK

Aufreinigung: SDS-PAGE

Reinheit: > 90 %

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.1-2 mg/mL

Buffer: 20 mM Tris-HCl based buffer, pH 8.0

Lagerung: -80 °C,4 °C,-20 °C

Informationen zur Lagerung: Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

Antigendetails

Target: HIST1H2BD (Histone Cluster 1, H2bd (HIST1H2BD))

Andere Bezeichnung: H2B1B (HIST1H2BD Produkte)

Synonyme: HIST1H2BI Protein, H2B.1B Protein, H2B/b Protein, H2BFB Protein, HIRIP2 Protein, dJ221C16.6 Protein, histone cluster 1, H2bd Protein, histone cluster 1 H2B family member d Protein, HIST1H2BD Protein

Hintergrund: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a tplate. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome rodeling.

Molekulargewicht: 29.81 kDa

UniProt: P33778

Pathways: Telomere Maintenance