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HAS2 Protein (AA 67-374, Cytoplasmic Domain, Cytosolic) (His tag)

HAS2 Spezies: Maus Wirt: Escherichia coli (E. coli) Recombinant > 90 % SDS
Produktnummer ABIN5709643
  • Target Alle HAS2 Proteine anzeigen
    HAS2 (Hyaluronan Synthase 2 (HAS2))
    Protein-Typ
    Recombinant
    Proteineigenschaft
    Cytosolic, AA 67-374, Cytoplasmic Domain
    Spezies
    • 4
    • 3
    Maus
    Quelle
    • 2
    • 2
    • 1
    • 1
    • 1
    Escherichia coli (E. coli)
    Aufreinigungstag / Konjugat
    Dieses HAS2 Protein ist gelabelt mit His tag.
    Applikation
    SDS-PAGE (SDS)
    Sequenz
    EHRKMKKSLE TPIKLNKTVA LCIAAYQEDP DYLRKCLQSV KRLTYPGIKV VMVIDGNSDD DLYMMDIFSE VMGRDKSATY IWKNNFHEKG PGETEESHKE SSQHVTQLVL SNKSICIMQK WGGKREVMYT AFRALGRSVD YVQVCDSDTM LDPASSVEMV KVLEEDPMVG GVGGDVQILN KYDSWISFLS SVRYWMAFNI ERACQSYFGC VQCISGPLGM YRNSLLHEFV EDWYNQEFMG NQCSFGDDRH LTNRVLSLGY ATKYTARSKC LTETPIEYLR WLNQQTRWSK SYFREWLYNA MWFHKHHL
    Aufreinigung
    SDS-PAGE
    Reinheit
    > 90 %
    Top Product
    Discover our top product HAS2 Protein
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    0.1-2 mg/mL
    Buffer
    20 mM Tris-HCl based buffer, pH 8.0
    Lagerung
    -80 °C,4 °C,-20 °C
    Informationen zur Lagerung
    Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Target
    HAS2 (Hyaluronan Synthase 2 (HAS2))
    Andere Bezeichnung
    HYAS2 (HAS2 Produkte)
    Synonyme
    DG42 Protein, XHas2 Protein, Has2 Protein, hyaluronan synthase 2 Protein, hyaluronan synthase 2 S homeolog Protein, has2 Protein, HAS2 Protein, Has2 Protein, SHAS2 Protein, has2.S Protein
    Hintergrund
    Catalyzes the addition of GlcNAc or GlcUA monosaccharides to the nascent hyaluronan polymer. Therefore, it is essential to hyaluronan synthesis a major component of most extracellular matrices that has a structural role in tissues architectures and regulates cell adhesion, migration and differentiation. This is one of the isozymes catalyzing that reaction and it is particularly responsible for the synthesis of high molecular mass hyaluronan. Required for the transition of endocardial cushion cells into mesenchymal cells, a process crucial for heart development. May also play a role in vasculogenesis. High molecular mass hyaluronan also play a role in early contact inhibition a process which stops cell growth when cells come into contact with each other or the extracellular matrix.
    Molekulargewicht
    40 kDa
    UniProt
    P70312
    Pathways
    Glycosaminoglycan Metabolic Process
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