FAIM3 Protein (AA 18-262, Extracellular) (His-SUMO Tag)

Produktnummer ABIN5709493

Produktdetails

Target: FAIM3 (Fas Apoptotic Inhibitory Molecule 3 (FAIM3))

Protein-Typ: Recombinant

Proteineigenschaft: Extracellular, AA 18-262

Spezies: Maus

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses FAIM3 Protein ist gelabelt mit His-SUMO Tag.

Applikation: SDS-PAGE (SDS)

Sequenz: RVLPEVQLNV EWGGSIIIEC PLPQLHVRMY LCRQMAKPGI CSTVVSNTFV KKEYERRVTL TPCLDKKLFL VEMTQLTEND DGIYACGVGM KTDKGKTQKI TLNVHNEYPE PFWEDEWTSE RPRWLHRFLQ HQMPWLHGSE HPSSSGVIAK VTTPAPKTEA PPVHQPSSIT SVTQHPRVYR AFSVSATKSP ALLPATTASK TSTQQAIRPL EASYSHHTRL HEQRTRHHGP HYGREDRGLH IPIPE

Aufreinigung: SDS-PAGE

Reinheit: > 90 %

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.1-2 mg/mL

Buffer: 20 mM Tris-HCl based buffer, pH 8.0

Lagerung: -80 °C,4 °C,-20 °C

Informationen zur Lagerung: Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

Antigendetails

Target: FAIM3 (Fas Apoptotic Inhibitory Molecule 3 (FAIM3))

Andere Bezeichnung: FAIM3 (FAIM3 Produkte)

Synonyme: FAIM3 Protein, FCMR Protein, TOSO Protein, 1810037B05Rik Protein, FcmuR Protein, Toso Protein, Fc fragment of IgM receptor Protein, FCMR Protein, Fcmr Protein

Hintergrund: May play a role in the immune syst processes. Protects cells from FAS-, TNF alpha- and FADD-induced apoptosis without increasing expression of the inhibitors of apoptosis BCL2 and BCLXL. Ses to activate an inhibitory pathway that prevents CASP8 activation following FAS stimulation, rather than blocking apoptotic signals downstream. May inhibit FAS-induced apoptosis by preventing CASP8 processing through CFLAR up-regulation .

Molekulargewicht: 43.9 kDa

UniProt: A1KXC4