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CRHR1 Protein (AA 24-121) (GST tag)

CRHR1 Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant > 90 % SDS
Produktnummer ABIN5709325
  • Target Alle CRHR1 Proteine anzeigen
    CRHR1 (Corticotropin Releasing Hormone Receptor 1 (CRHR1))
    Protein-Typ
    Recombinant
    Proteineigenschaft
    AA 24-121
    Spezies
    • 6
    • 2
    • 1
    Human
    Quelle
    • 4
    • 3
    • 1
    • 1
    Escherichia coli (E. coli)
    Aufreinigungstag / Konjugat
    Dieses CRHR1 Protein ist gelabelt mit GST tag.
    Applikation
    SDS-PAGE (SDS)
    Sequenz
    SLQDQHCESL SLASNISGLQ CNASVDLIGT CWPRSPAGQL VVRPCPAFFY GVRYNTTNNG YRECLANGSW AARVNYSECQ EILNEEKKSK VHYHVAVI
    Aufreinigung
    SDS-PAGE
    Reinheit
    > 90 %
    Top Product
    Discover our top product CRHR1 Protein
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    0.1-2 mg/mL
    Buffer
    20 mM Tris-HCl based buffer, pH 8.0
    Lagerung
    -80 °C,4 °C,-20 °C
    Informationen zur Lagerung
    Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Target
    CRHR1 (Corticotropin Releasing Hormone Receptor 1 (CRHR1))
    Andere Bezeichnung
    CRFR1 (CRHR1 Produkte)
    Synonyme
    CRF-R Protein, CRF-R-1 Protein, CRF-R1 Protein, CRF1 Protein, CRFR-1 Protein, CRFR1 Protein, CRH-R-1 Protein, CRH-R1 Protein, CRH-R1h Protein, CRHR Protein, CRHR1L Protein, CRHR1f Protein, Crhr Protein, crhr1 Protein, crhr1-A Protein, CRHR1 Protein, CRHR1-IT1-CRHR1 Protein, MGC57346-CRHR1 Protein, corticotropin releasing hormone receptor 1 Protein, corticotropin releasing hormone receptor 1, gene 2 S homeolog Protein, corticotropin-releasing factor receptor 1 Protein, LINC02210-CRHR1 readthrough Protein, CRHR1 Protein, Crhr1 Protein, crhr1.2.S Protein, LOC610380 Protein, LOC100065598 Protein, LINC02210-CRHR1 Protein, crhr1 Protein
    Hintergrund
    G-protein coupled receptor for CRH (corticotropin-releasing factor) and UCN (urocortin). Has high affinity for CRH and UCN. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and down-stream effectors, such as adenylate cyclase. Promotes the activation of adenylate cyclase, leading to increased intracellular cAMP levels. Inhibits the activity of the calcium channel CACNA1H. Required for normal bryonic development of the adrenal gland and for normal hormonal responses to stress. Plays a role in the response to anxiogenic stimuli.
    Molekulargewicht
    38.3 kDa
    UniProt
    P34998
    Pathways
    Hormone Transport, cAMP Metabolic Process, Myometrial Relaxation and Contraction, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Feeding Behaviour, Negative Regulation of Transporter Activity
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