ATP5A1 Protein (AA 44-553) (His-SUMO Tag)

Produktnummer ABIN5709103

Produktdetails

Target: ATP5A1 (ATP Synthase, H+ Transporting, Mitochondrial F1 Complex, alpha Subunit 1, Cardiac Muscle (ATP5A1))

Protein-Typ: Recombinant

Proteineigenschaft: AA 44-553

Spezies: Human

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses ATP5A1 Protein ist gelabelt mit His-SUMO Tag.

Applikation: SDS-PAGE (SDS)

Sequenz: QKTGTAEMSS ILEERILGAD TSVDLEETGR VLSIGDGIAR VHGLRNVQAE EMVEFSSGLK GMSLNLEPDN VGVVVFGNDK LIKEGDIVKR TGAIVDVPVG EELLGRVVDA LGNAIDGKGP IGSKTRRRVG LKAPGIIPRI SVREPMQTGI KAVDSLVPIG RGQRELIIGD RQTGKTSIAI DTIINQKRFN DGSDEKKKLY CIYVAIGQKR STVAQLVKRL TDADAMKYTI VVSATASDAA PLQYLAPYSG CSMGEYFRDN GKHALIIYDD LSKQAVAYRQ MSLLLRRPPG REAYPGDVFY LHSRLLERAA KMNDAFGGGS LTALPVIETQ AGDVSAYIPT NVISITDGQI FLETELFYKG IRPAINVGLS VSRVGSAAQT RAMKQVAGTM KLELAQYREV AAFAQFGSDL DAATQQLLSR GVRLTELLKQ GQYSPMAIEE QVAVIYAGVR GYLDKLEPSK ITKFENAFLS HVVSQHQALL GTIRADGKIS EQSDAKLKEI VTNFLAGFEA

Aufreinigung: SDS-PAGE

Reinheit: > 90 %

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.1-2 mg/mL

Buffer: 20 mM Tris-HCl based buffer, pH 8.0

Lagerung: -80 °C,4 °C,-20 °C

Informationen zur Lagerung: Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

Antigendetails

Target: ATP5A1 (ATP Synthase, H+ Transporting, Mitochondrial F1 Complex, alpha Subunit 1, Cardiac Muscle (ATP5A1))

Andere Bezeichnung: ATPA (ATP5A1 Produkte)

Synonyme: atp5a Protein, MGC108350 Protein, AI035633 Protein, AL022851 Protein, AL023067 Protein, Atpm Protein, D18Ertd206e Protein, Mom2 Protein, ATP5A Protein, ATP5AL2 Protein, ATPM Protein, MC5DN4 Protein, MOM2 Protein, OMR Protein, ORM Protein, hATP1 Protein, zgc:154103 Protein, ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle L homeolog Protein, ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle Protein, ATP synthase subunit alpha, mitochondrial Protein, ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1 Protein, atp5a1.L Protein, ATP5A1 Protein, atp5a1 Protein, LOC100395383 Protein, Atp5a1 Protein

Hintergrund: Mitochondrial membrane ATP synthase (F1F0 ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the mbrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F1 - containing the extrambraneous catalytic core, and F0 - containing the mbrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F1 is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Subunits alpha and beta form the catalytic core in F1. Rotation of the central stalk against the surrounding alpha3beta3 subunits leads to hydrolysis of ATP in three separate catalytic sites on the beta subunits. Subunit alpha does not bear the catalytic high-affinity ATP-binding sites .

Molekulargewicht: 71.18 kDa

UniProt: P25705

Pathways: Proton Transport, Ribonucleoside Biosynthetic Process