LRRC32 Protein (AA 20-627) (Fc Tag)
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- Target Alle LRRC32 Proteine anzeigen
- LRRC32 (Leucine Rich Repeat Containing 32 (LRRC32))
- Protein-Typ
- Recombinant
- Proteineigenschaft
- AA 20-627
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Spezies
- Human
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Quelle
- HEK-293 Cells
- Aufreinigungstag / Konjugat
- Dieses LRRC32 Protein ist gelabelt mit Fc Tag.
- Sequenz
- AA 20-627
- Produktmerkmale
- This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 92.6 kDa. The protein migrates as 35 kDa and 100-116 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
- Reinheit
- >95 % as determined by SDS-PAGE.
- Endotoxin-Niveau
- Less than 1.0 EU per μg by the LAL method.
- Top Product
- Discover our top product LRRC32 Protein
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Leucine Rich Repeat Containing 32 (LRRC32) protein (Fc Tag)
LRRC32 Spezies: Human Wirt: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
Leucine Rich Repeat Containing 32 (LRRC32) (AA 20-627) protein (His tag)Crystallography grade LRRC32 Spezies: Human Wirt: Insektenzellen Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Leucine Rich Repeat Containing 32 (LRRC32) (AA 20-662) protein (rho-1D4 tag)Crystallography grade LRRC32 Spezies: Human Wirt: Insektenzellen Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Leucine Rich Repeat Containing 32 (LRRC32) proteinLRRC32 Spezies: Maus Wirt: Escherichia coli (E. coli) Recombinant > 95 % WB, SDS, ELISA, IP
Leucine Rich Repeat Containing 32 (LRRC32) (Transcript Variant 1) protein (Myc-DYKDDDDK Tag)LRRC32 Spezies: Human Wirt: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Buffer
- Tris with Glycine, Arginine and NaCl, pH 7.5
- Handhabung
- Please avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
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- Target
- LRRC32 (Leucine Rich Repeat Containing 32 (LRRC32))
- Andere Bezeichnung
- LRRC32 (LRRC32 Produkte)
- Synonyme
- D11S833E Protein, GARP Protein, AI426318 Protein, D11S833Eh Protein, D7H11S833E Protein, EG434215 Protein, Garp Protein, leucine rich repeat containing 32 Protein, LRRC32 Protein, Lrrc32 Protein
- Hintergrund
- Leucine-rich repeat protein 32 (LRRC32), also known as GARP (glycoprotein A repetitions predominant). LRRC32 expression promotes the acquisition of a Treg phenotype including reduced cellular proliferation, reduced cytokine secretion, and the capacity to suppress the proliferation of naive T cells. LRRC32 binds directly to the TGF-beta latency associated peptide (LAP) and tethers latent TGF-beta on the surface of activated Treg cells. The presentation of TGF-beta on Tregs contributes to their ability to suppress naive T cell proliferation.
- Molekulargewicht
- 92.4 kDa
- NCBI Accession
- NP_005503
- Pathways
- Activated T Cell Proliferation
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