CD58 Protein (CD58) (partial) (Fc Tag)
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- Target Alle CD58 Proteine anzeigen
- CD58
- Protein-Typ
- Recombinant
- Biologische Aktivität
- Active
- Proteineigenschaft
- partial
- Spezies
- Human
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Quelle
- HEK-293 Cells
- Aufreinigungstag / Konjugat
- Dieses CD58 Protein ist gelabelt mit Fc Tag.
- Applikation
- Western Blotting (WB), ELISA
- Sequenz
- Phe 29 - Arg 215
- Reinheit
- >95 % as determined by SDS-PAGE.
- Endotoxin-Niveau
- Endotoxin level is less than 1.0 EU per ug by the LAL method.
- Biological Activity Comment
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Measured by its binding ability in a functional ELISA. Immobilized Human CD2, His Tag at 2 μg/mL (100 uL/well) can bind Human CD58, Fc Tag with a linear range of 10-156 ng/mL (QC tested).
- Top Product
- Discover our top product CD58 Protein
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- Applikationshinweise
- This recombinant protein can be used for E, WB.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Buffer
- 50 mM Tris, 100 mM Glycine, pH 7.5
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C,-80 °C
- Informationen zur Lagerung
- Lyophilized Protein should be stored at -20°C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20°C or -70°C.
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- Target
- CD58
- Andere Bezeichnung
- CD58 (CD58 Produkte)
- Synonyme
- LFA-3 Protein, LFA3 Protein, ag3 Protein, CD58 molecule Protein, CD58 Protein
- Hintergrund
- CD antigen CD58 is also known as Lymphocyte function-associated antigen 3 (LFA-3). CD58 is a cell adhesion molecule expressed on Antigen Presenting Cells (APC), particularly macrophages. CD58 /LFA3 is ligand of the T-lymphocyte CD2 glycoprotein, which binds to CD2 (LFA-2) [3] on T cells and is important in strengthening the adhesion between the T cells and Professional Antigen Presenting Cells. In addition, the LFA-3/CD2 interaction may prime response by both the CD2+ and LFA-3+ cells. Polymorphisms in the CD58 gene are associated with increased risk for multiple sclerosis.
- Molekulargewicht
- 48.1 kDa
- Gen-ID
- 965
- UniProt
- Q9BRW0
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