GFI1B Protein (His tag)

Produktnummer ABIN5505652

Produktdetails

Target: GFI1B (Growth Factor Independent 1B Transcription Repressor (GFI1B))

Protein-Typ: Recombinant

Spezies: Human

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses GFI1B Protein ist gelabelt mit His tag.

Applikation: Antibody Production (AbP), Standard (STD)

Produktmerkmale:

• Recombinant human Purified recombinant protein of Human growth factor independent 1B transcription repressor (GFI1B), transcript variant 2, full length, with N-terminal HIS tag, expressed in E. coli, 50 μg (full length, N-term HIS tag, transcript variant 2) protein expressed in E.coli.
• Produced with end-sequenced ORF clone

Aufreinigung: Purified

Reinheit: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Anwendungsinformationen

Applikationshinweise: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Kommentare:

The tag is located at the N-terminal.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 50 μg/mL

Buffer: 25 mM Tris, pH 8.0, 150 mM NaCl, 10 % glycerol, 1 % Sarkosyl.

Lagerung: -80 °C

Informationen zur Lagerung: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Antigendetails

Target: GFI1B (Growth Factor Independent 1B Transcription Repressor (GFI1B))

Andere Bezeichnung: growth factor independent 1B transcription repressor (GFI1B Produkte)

Synonyme: GFI1B Protein, GFI Protein, znf544 Protein, MGC80648 Protein, Gfi-1B Protein, growth factor independent 1B transcriptional repressor Protein, growth factor independent 1B transcription repressor L homeolog Protein, Zinc finger protein Gfi-1b Protein, growth factor independent 1B Protein, GFI1B Protein, Gfi1b Protein, gfi1b.L Protein, gfi1b Protein

Hintergrund: This gene encodes a zinc-finger containing transcriptional regulator that is primarily expressed in cells of hematopoietic lineage. The encoded protein complexes with numerous other transcriptional regulatory proteins including GATA-1, runt-related transcription factor 1 and histone deacetylases to control expression of genes involved in the development and maturation of erythrocytes and megakaryocytes. Mutations in this gene are the cause of the autosomal dominant platelet disorder, platelet-type bleeding disorder-17. Alternate splicing results in multiple transcript variants.

Molekulargewicht: 32.2 kDa

NCBI Accession: NP_001128503

Pathways: Cellular Response to Molecule of Bacterial Origin