HMGCS2 Protein (His tag)

Produktnummer ABIN5505541

Produktdetails

Target: HMGCS2 (3-Hydroxy-3-Methylglutaryl-CoA Synthase 2 (Mitochondrial) (HMGCS2))

Protein-Typ: Recombinant

Spezies: Human

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses HMGCS2 Protein ist gelabelt mit His tag.

Applikation: Antibody Production (AbP), Standard (STD)

Produktmerkmale:

• Recombinant human Purified recombinant protein of Human 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial) (HMGCS2), nuclear gene encoding mitochondrial protein, transcript variant 2, full length, with N-terminal HIS tag, expressed in E.coli, 50 μg (full length, N-term HIS tag, transcript variant 2) protein expressed in E.coli.
• Produced with end-sequenced ORF clone

Aufreinigung: Purified

Reinheit: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Anwendungsinformationen

Applikationshinweise: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Kommentare:

The tag is located at the N-terminal.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 50 μg/mL

Buffer: 25 mM Tris, pH 8.0, 150 mM NaCl, 10 % glycerol, 1 % Sarkosyl.

Lagerung: -80 °C

Informationen zur Lagerung: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Antigendetails

Target: HMGCS2 (3-Hydroxy-3-Methylglutaryl-CoA Synthase 2 (Mitochondrial) (HMGCS2))

Andere Bezeichnung: 3-hydroxy-3-methylglutaryl-CoA synthase 2 (HMGCS2 Produkte)

Synonyme: 1300002P16 Protein, mHS Protein, DDBDRAFT_0219349 Protein, DDBDRAFT_0219924 Protein, DDB_0219349 Protein, DDB_0219924 Protein, Hmgcs1 Protein, Mt3h3mg Protein, hmgCoA Protein, 3-hydroxy-3-methylglutaryl-CoA synthase 2 Protein, 3-hydroxy-3-methylglutaryl-Coenzyme A synthase 2 Protein, hydroxymethylglutaryl-CoA synthase Protein, hydroxymethylglutaryl-coa synthase Protein, 3-HYDROXY-3-METHYLGLUTARYL-CoA SYNTHASE 2 Protein, HMGCS2 Protein, Hmgcs2 Protein, mvaS Protein, CNC05080 Protein, HMCS1 Protein, hgsA Protein, MFER_RS00425 Protein, LOC100285783 Protein, ECU10_0510 Protein, Eint_100450 Protein

Hintergrund: The protein encoded by this gene belongs to the HMG-CoA synthase family. It is a mitochondrial enzyme that catalyzes the first reaction of ketogenesis, a metabolic pathway that provides lipid-derived energy for various organs during times of carbohydrate deprivation, such as fasting. Mutations in this gene are associated with HMG-CoA synthase deficiency. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Oct 2009].

Molekulargewicht: 48.2 kDa

NCBI Accession: NP_001159579

Pathways: Response to Growth Hormone Stimulus, Cellular Response to Molecule of Bacterial Origin, Regulation of Lipid Metabolism by PPARalpha