MGAT2 Protein (AA 30-447) (His tag)

Produktnummer ABIN4370687

Produktdetails

Target: MGAT2 (Mannosyl (Alpha-1,6-)-Glycoprotein beta-1,2-N-Acetylglucosaminyltransferase (MGAT2))

Protein-Typ: Recombinant

Proteineigenschaft: AA 30-447

Spezies: Human

Quelle: Human Cells

Aufreinigungstag / Konjugat: Dieses MGAT2 Protein ist gelabelt mit His tag.

Verwendungszweck: Recombinant Human Mannoside Acetylglucosaminyltransferase 2/GlcNAc-TII (C-6His)

Sequenz: RQRKNEALAP PLLDAEPARG AGGRGGDHPS VAVGIRRVSN VSAASLVPAV PQPEADNLTL RYRSLVYQLN FDQTLRNVDK AGTWAPRELV LVVQVHNRPE YLRLLLDSLR KAQGIDNVLV IFSHDFWSTE INQLIAGVNF CPVLQVFFPF SIQLYPNEFP GSDPRDCPRD LPKNAALKLG CINAEYPDSF GHYREAKFSQ TKHHWWWKLH FVWERVKILR DYAGLILFLE EDHYLAPDFY HVFKKMWKLK QQECPECDVL SLGTYSASRS FYGMADKVDV KTWKSTEHNM GLALTRNAYQ KLIECTDTFC TYDDYNWDWT LQYLTVSCLP KFWKVLVPQI PRIFHAGDCG MHHKKTCRPS TQSAQIESLL NNNKQYMFPE TLTISEKFTV VAISPPRKNG GWGDIRDHEL CKSYRRLQLD HHHHHH

Produktmerkmale: Recombinant Human Mannoside Acetylglucosaminyltransferase 2/MGAT2 is produced by our mammalian expression system in human cells. The target protein is expressed with sequence (Arg30-Gln447) of Human MGAT2 fused with a 6His tag at the C-terminus.

Reinheit: > 95 % as determined by reducing SDS-PAGE.

Sterilität: 0.2 μm filtered

Endotoxin-Niveau: Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Rekonstitution: It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Buffer: Supplied as a 0.2 μm filtered solution of 20 mM TrisHCl,150 mM NaCl, pH 8.0 .

Handhabung: Always centrifuge tubes before opening. Do not mix by vortex or pipetting.

Lagerung: -80 °C

Informationen zur Lagerung: Store at < -20°C, stable for 6 months after receipt.
Please minimize freeze-thaw cycles.

Haltbarkeit: 6 months

Antigendetails

Target: MGAT2 (Mannosyl (Alpha-1,6-)-Glycoprotein beta-1,2-N-Acetylglucosaminyltransferase (MGAT2))

Andere Bezeichnung: GlcNAc-T-II (MGAT2 Produkte)

Synonyme: CDG2A Protein, CDGS2 Protein, GLCNACTII Protein, GNT-II Protein, GNT2 Protein, CG7921 Protein, Dmel\\CG7921 Protein, GlcNAc-TII Protein, GlcNAcT2 Protein, dMGAT2 Protein, MGC89475 Protein, Gnt2 Protein, AA407964 Protein, CH73-301C19.1 Protein, zgc:162268 Protein, mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase Protein, CG7921 gene product from transcript CG7921-RB Protein, mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase L homeolog Protein, mannoside acetylglucosaminyltransferase 2 Protein, MGAT2 Protein, Mgat2 Protein, mgat2.L Protein, mgat2 Protein

Sub Type: Fusionprotein

Hintergrund: Mannoside Acetylglucosaminyltransferase 2 (MGAT2) is a single-pass type II membrane protein that contains the typical glycosyltransferase domains: a short N-terminal cytoplasmic domain, a hydrophobic non-cleavable signal-anchor domain and a C-terminal catalytic domain. MGAT2 catalyzes an essential step in the conversion of oligo-mannose to complex N-glycans. Defects in MGAT2 are the cause of congenital disorder of glycosylation type 2A.
Alternative Names: Alpha-1,6-Mannosyl-Glycoprotein 2-Beta-N-Acetylglucosaminyltransferase, Beta-1,2-N-acetylglucosaminyltransferase II, GlcNAc-T II, NT-II, Mannoside Acetylglucosaminyltransferase 2, N-Glycosyl-Oligosaccharide-Glycoprotein N-Acetylglucosaminyltransferase II,

Molekulargewicht: 49.3 kDa

UniProt: Q10469