MPZ Protein (AA 30-153) (His tag)

Produktnummer ABIN4370664

Produktdetails

Target: MPZ (Myelin Protein Zero (MPZ))

Protein-Typ: Recombinant

Proteineigenschaft: AA 30-153

Spezies: Human

Quelle: Human Cells

Aufreinigungstag / Konjugat: Dieses MPZ Protein ist gelabelt mit His tag.

Verwendungszweck: Recombinant Human Myelin Protein P0/MPZ (C-6His)

Sequenz: IVVYTDREVH GAVGSRVTLH CSFWSSEWVS DDISFTWRYQ PEGGRDAISI FHYAKGQPYI DEVGTFKERI QWVGDPRWKD GSIVIHNLDY SDNGTFTCDV KNPPDIVGKT SQVTLYVFEK VPTRVDHHHH HH

Produktmerkmale: Recombinant Human Myelin Protein P0/MPZ is produced by our mammalian expression system in human cells. The target protein is expressed with sequence (Ile30-Arg153) of Human MPZ fused with a 6His tag at the C-terminus.

Reinheit: > 95 % as determined by reducing SDS-PAGE.

Sterilität: 0.2 μm filtered

Endotoxin-Niveau: Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Buffer: Lyophilized from a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl, pH 7.2.

Handhabung: Always centrifuge tubes before opening. Do not mix by vortex or pipetting.

Lagerung: 4 °C/-20 °C/-80 °C

Informationen zur Lagerung: Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Haltbarkeit: 3 months

Antigendetails

Target: MPZ (Myelin Protein Zero (MPZ))

Andere Bezeichnung: Myelin-protein-P0 (MPZ Produkte)

Synonyme: CHM Protein, CMT1 Protein, CMT1B Protein, CMT2I Protein, CMT2J Protein, CMT4E Protein, CMTDI3 Protein, CMTDID Protein, DSS Protein, HMSNIB Protein, MPP Protein, P0 Protein, Mpp Protein, P-zero Protein, p0 Protein, sc:d0186 Protein, wu:fc04b11 Protein, wu:fi30g06 Protein, zgc:103775 Protein, myelin protein zero Protein, myelin protein zero S homeolog Protein, MPZ Protein, Mpz Protein, mpz Protein, mpz.S Protein

Sub Type: Fusionprotein

Hintergrund: Myelin Protein P0 (MPZ) is a single-pass type I membrane glycoprotein which belongs to the myelin P0 protein family. MPZ contains one Ig-like V-type (immunoglobulin-like) domain, absent in the central nervous system. MPZ is a major component of the myelin sheath in peripheral nerves. It is postulated that MPZ is a structural element in the formation and stabilisation of peripheral nerve myelin, holding its characteristic coil structure together by the interaction of its positively-charged domain with acidic lipids in the cytoplasmic face of the opposed bilayer, and by interaction between hydrophobic globular of adjacent extracellular domains. Defects in MPZ associated with Charcot-Marie-Tooth disease and Dejerine-Sottas disease.
Alternative Names: Myelin Protein P0, Myelin Peripheral Protein, MPP, Myelin Protein Zero, MPZ

Molekulargewicht: 15.2 kDa

UniProt: P25189