CSF3R Protein (AA 25-621) (His tag,AVI tag,Biotin)

Produktnummer ABIN3137667

Produktdetails

Target: CSF3R (Colony Stimulating Factor 3 Receptor (Granulocyte) (CSF3R))

Protein-Typ: Recombinant

Biologische Aktivität: Active

Proteineigenschaft: AA 25-621

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses CSF3R Protein ist gelabelt mit His tag,AVI tag,Biotin.

Marke: MABSol®,PrecisionAvi

Sequenz: AA 25-621

Spezifität: Biotinylation of this product is performed using Avitag™ technology. Briefly, the single lysine residue in the Avitag is enzymatically labeled with biotin.

Produktmerkmale: This protein carries an Avi tag (Avitag™) at the C-terminus, followed by a polyhistidine tag. The protein has a calculated MW of 69.2 kDa. The protein migrates as 72-85 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

Reinheit: >95 % as determined by SDS-PAGE.

Endotoxin-Niveau: Less than 1.0 EU per μg by the LAL method.

Anwendungsinformationen

Kommentare:

Ready-to-use AvitagTM biotinylated protein:
The product is exclusively produced using the AvitagTM technology. Briefly, a unique 15 amino acid peptide, the Avi tag, is introduced into the recombinant protein during expression vector construction. The single lysine residue in the Avi tag is enzymatically biotinylated by the E. Coli biotin ligase BirA.

This single-point enzymatic labeling technique brings many advantages for commonly used binding assays. The biotinylation happens on the lysine residue of Avi tag, and therefore does NOT interfere with the target protein's natural binding activities. In addition, when immobilized on an avidin-coated surface, the protein orientation is uniform because the position of the Avi tag in the protein is precisely controlled.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: PBS, pH 7.4

Handhabung: Please avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Antigendetails

Target: CSF3R (Colony Stimulating Factor 3 Receptor (Granulocyte) (CSF3R))

Andere Bezeichnung: G-CSFR (CSF3R Produkte)

Synonyme: CD114 Protein, GCSFR Protein, Cd114 Protein, Csfgr Protein, G-CSF-R Protein, G-CSFR Protein, CSF3R Protein, gcsfr Protein, cd114 Protein, colony stimulating factor 3 receptor Protein, colony stimulating factor 3 receptor (granulocyte) Protein, colony stimulating factor 3 receptor L homeolog Protein, granulocyte colony-stimulating factor receptor Protein, CSF3R Protein, Csf3r Protein, csf3r Protein, csf3r.L Protein, LOC100433338 Protein

Hintergrund: The granulocyte colony-stimulating factor receptor (G-CSF-R) also known as CD114 (Cluster of Differentiation 114) is a protein that is encoded by the CSF3R gene. G-CSF-R is a cell-surface receptor for the granulocyte colony-stimulating factor (G-CSF). The G-CSF receptors belongs to a family of cytokine receptors known as the hematopoietin receptor family. Granulocyte colony-stimulating factor receptor has been shown to interact with Grb2, HCK and SHC1. The granulocyte colony-stimulating factor receptor is present on precursor cells in the bone marrow, and, in response to stimulation by G-CSF, initiates cell proliferation and differentiation into mature neutrophilic granulocytes and macrophages.

Molekulargewicht: 69.2 kDa

NCBI Accession: NP_000751