Fibulin 5 Protein (FBLN5) (AA 1-448) (GST tag)

Produktnummer ABIN2752787

Produktdetails

Target: Fibulin 5 (FBLN5)

Protein-Typ: Recombinant

Proteineigenschaft: AA 1-448

Spezies: Human

Quelle: Wheat germ

Aufreinigungstag / Konjugat: Dieses Fibulin 5 Protein ist gelabelt mit GST tag.

Applikation: Western Blotting (WB), ELISA, Affinity Purification (AP), Antibody Array (AA)

Verwendungszweck: FBLN5 (Human) Recombinant Protein (P01)

Sequenz: MPGIKRILTV TILALCLPSP GNAQAQCTNG FDLDRQSGQC LDIDECRTIP EACRGDMMCV NQNGGYLCIP RTNPVYRGPY SNPYSTPYSG PYPAAAPPLS APNYPTISRP LICRFGYQMD ESNQCVDVDE CATDSHQCNP TQICINTEGG YTCSCTDGYW LLEGQCLDID ECRYGYCQQL CANVPGSYSC TCNPGFTLNE DGRSCQDVNE CATENPCVQT CVNTYGSFIC RCDPGYELEE DGVHCSDMDE CSFSEFLCQH ECVNQPGTYF CSCPPGYILL DDNRSCQDIN ECEHRNHTCN LQQTCYNLQG GFKCIDPIRC EEPYLRISDN RCMCPAENPG CRDQPFTILY RDMDVVSGRS VPADIFQMQA TTRYPGAYYI FQIKSGNEGR EFYMRQTGPI SATLVMTRPI KGPREIQLDL EMITVNTVIN FRGSSVIRLR IYVSQYPF

Produktmerkmale: Human FBLN5 full-length ORF (BAG52073.1, 1 a.a. - 448 a.a.) recombinant protein with GST tag at N-terminal.

Aufreinigung: in vitro wheat germ expression system

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH =8.0 in the elution buffer.

Handhabung: Aliquot to avoid repeated freezing and thawing.

Lagerung: -80 °C

Informationen zur Lagerung: Best use within three months from the date of receipt of this protein.

Antigendetails

Target: Fibulin 5 (FBLN5)

Andere Bezeichnung: FBLN5 (FBLN5 Produkte)

Synonyme: zgc:103575 Protein, FBLN5 Protein, MGC108414 Protein, Fibulin-5 Protein, DKFZp469K0327 Protein, ADCL2 Protein, ARCL1A Protein, ARMD3 Protein, DANCE Protein, EVEC Protein, FIBL-5 Protein, UP50 Protein, A55 Protein, fibulin 5 Protein, fbln5 Protein, FBLN5 Protein, Fbln5 Protein

Hintergrund: Synonyms: ARMD3,DANCE,EVEC,FIBL-5,FLJ90059,UP50
Gene Description: fibulin 5
Gene Name: FBLN5
Gene Summary: The protein encoded by this gene is a secreted, extracellular matrix protein containing an Arg-Gly-Asp (RGD) motif and calcium-binding EGF-like domains. It promotes adhesion of endothelial cells through interaction of integrins and the RGD motif. It is prominently expressed in developing arteries but less so in adult vessels. However, its expression is reinduced in balloon-injured vessels and atherosclerotic lesions, notably in intimal vascular smooth muscle cells and endothelial cells. Therefore, the protein encoded by this gene may play a role in vascular development and remodeling. Defects in this gene are a cause of autosomal dominant cutis laxa, autosomal recessive cutis laxa type I (CL type I), and age-related macular degeneration type 3 (ARMD3).
GenBank: AK075147.1, BAG52073.1

Molekulargewicht: 76.6 kDa (theoreatical)

Gen-ID: 10516

Pathways: SARS-CoV-2 Protein Interaktom