NADK Protein (His tag)
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- Target Alle NADK Proteine anzeigen
- NADK (NAD Kinase (NADK))
- Protein-Typ
- Recombinant
- Biologische Aktivität
- Active
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Spezies
- Mycobacterium tuberculosis
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Quelle
- Escherichia coli (E. coli)
- Aufreinigungstag / Konjugat
- Dieses NADK Protein ist gelabelt mit His tag.
- Applikation
- SDS-PAGE (SDS)
- Produktmerkmale
- NAD kinase (Mycobacterium tuberculosis) is fused at the N-terminus to a His-tag.
- Reinheit
- >98 % (SDS-PAGE)
- Top Product
- Discover our top product NADK Protein
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- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Kommentare
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~1.2 U/mg protein. (Substrate: NAD (+ ATP)) ~3.8 U/mg protein. (Substrate: NAD (+ poly(P)) One unit is defined as the amount of enzyme that synthesizes 1μmol nicotinamide adenine dinucleotide phosphate (NADP) per min.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- Liquid. In 10 mM TRIS at pH 8.0, containing 1 mM MgCl2, 0.5 mM EDTA, 1 mM DTT and 1 mM PMSF.
- Konservierungsmittel
- Dithiothreitol (DTT)
- Vorsichtsmaßnahmen
- This product contains Dithiothreitol (DTT): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C,-80 °C
- Informationen zur Lagerung
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Short Term Storage: -20°C
Long Term Storage: -80°C
Stable for at least 6 months after receipt when stored at -80°C. - Haltbarkeit
- 6 months
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- Target
- NADK (NAD Kinase (NADK))
- Andere Bezeichnung
- NAD Kinase (NADK Produkte)
- Synonyme
- 4432404C02Rik Protein, BC004012 Protein, dJ283E3.1 Protein, NAD kinase Protein, Nadk Protein, NADK Protein
- Hintergrund
- NAD kinase catalyzes the transfer of a phosphate group from ATP to NAD+ to generate NADP+, which in its reduced form acts as an electron donor for biosynthetic reactions. NADP+ is an essential coenzyme in metabolism and provides reducing power to biosynthetic processes such as fatty acid biosynthesis. NAD kinase from Mycobacterium tuberculosis is not ATP-dependent but has a broader substrate specificity than human NAD kinase. It can economically produce NADP+ by using other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus. Was identified as a high-confidence drug target. Catalytic activity: ATP + NAD+ = ADP + NADP+
- Molekulargewicht
- ~33.0kDa
- UniProt
- P0A5S6
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