JAG2 Protein (AA 1-1054) (Fc Tag)
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- Target Alle JAG2 Proteine anzeigen
- JAG2 (Jagged 2 (JAG2))
- Protein-Typ
- Recombinant
- Proteineigenschaft
- AA 1-1054
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Spezies
- Human
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Quelle
- HEK-293 Cells
- Aufreinigungstag / Konjugat
- Dieses JAG2 Protein ist gelabelt mit Fc Tag.
- Applikation
- SDS-PAGE (SDS)
- Kreuzreaktivität
- Human
- Produktmerkmale
- Human Jagged-2 (aa 1-1054) is fused at the C-terminus to the Fc portion of human IgG.
- Reinheit
- >90 % (SDS-PAGE)
- Endotoxin-Niveau
- <0.1EU/μg purified protein (LAL test, Lonza).
- Top Product
- Discover our top product JAG2 Protein
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- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Rekonstitution
- Reconstitute with 100 μL sterile water.
- Konzentration
- Lot specific
- Buffer
- Lyophilized. Contains PBS + 0.02 % CHAPS.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
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Short Term Storage: +4°C
Long Term Storage: -20°C
Stable for at least 6 months after receipt when stored at -20°C. - Haltbarkeit
- 6 months
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- Target
- JAG2 (Jagged 2 (JAG2))
- Andere Bezeichnung
- Jagged-2 (JAG2 Produkte)
- Synonyme
- D12Ggc2e Protein, Serh Protein, mJagged2-1 Protein, sm Protein, HJ2 Protein, SER2 Protein, jag2 Protein, serB Protein, zgc:152855 Protein, jagged 2 Protein, jagged 2b Protein, JAG2 Protein, jag2 Protein, Jag2 Protein, jag2b Protein
- Hintergrund
- Jagged-2 is a putative Notch ligand involved in the mediation of Notch signaling, that can induce stromal cells to secrete IL-6, VEGF and IGF-1. Notch activation can interact with NF-kappaB and C-myc to promote the proliferation and to inhibit the apoptosis of MM cells, showing in the relationship between the incidence of myeloma and drug resistance. Jagged-2 is also involved in limb development.
- Molekulargewicht
- ~150kDa (SDS-PAGE)
- UniProt
- Q9Y219
- Pathways
- Notch Signalweg, Sensory Perception of Sound
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