XRCC6BP1 Protein (His tag)

Produktnummer ABIN2735703

Produktdetails

Target: XRCC6BP1 (XRCC6 Binding Protein 1 (XRCC6BP1))

Protein-Typ: Recombinant

Spezies: Human

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses XRCC6BP1 Protein ist gelabelt mit His tag.

Applikation: Antibody Production (AbP), Standard (STD)

Produktmerkmale:

• Recombinant human XRCC6BP1 / KUBP (full length, N-term HIS tag) protein expressed in E. coli.
• Produced with end-sequenced ORF clone

Reinheit: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Anwendungsinformationen

Applikationshinweise: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Kommentare:

The tag is located at the N-terminal.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 50 μg/mL

Buffer: 25 mM Tris, pH 8.0, 150 mM NaCl, 10 % glycerol, 1 % Sarkosyl. Store at -80C. Avoid repeated freeze-thaw cycles. Stable for at least 3 months from receipt of products under proper storage and handling conditions.

Lagerung: -80 °C

Informationen zur Lagerung: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Antigendetails

Target: XRCC6BP1 (XRCC6 Binding Protein 1 (XRCC6BP1))

Andere Bezeichnung: Xrcc6bp1,kubp (XRCC6BP1 Produkte)

Synonyme: XRCC6BP1 Protein, MGC108292 Protein, KUB3 Protein, 1110068E08Rik Protein, 2410012H02Rik Protein, kub3 Protein, MGC69108 Protein, ATP23 metallopeptidase and ATP synthase assembly factor homolog Protein, XRCC6 binding protein 1 Protein, ATP23 metallopeptidase and ATP synthase assembly factor homolog L homeolog Protein, Atp23 Protein, ATP23 Protein, atp23 Protein, Xrcc6bp1 Protein, atp23.L Protein

Hintergrund: The protein encoded by this gene is amplified in glioblastomas and interacts with the DNA binding subunit of DNA-dependent protein kinase. This kinase is involved in double-strand break repair (DSB), and higher expression of the encoded protein increases the efficiency of DSB. In addition, comparison to orthologous proteins strongly suggests that this protein is a metalloprotease important in the biosynthesis of mitochondrial ATPase. Several transcript variants encoding different isoforms have been found for this gene.

Molekulargewicht: 28.1 kDa

NCBI Accession: NP_150592