VPREB3 Protein (Myc-DYKDDDDK Tag)

Produktnummer ABIN2735411

Produktdetails

Target: VPREB3 (Pre-B Lymphocyte 3 (VPREB3))

Protein-Typ: Recombinant

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses VPREB3 Protein ist gelabelt mit Myc-DYKDDDDK Tag.

Applikation: Antibody Production (AbP), Standard (STD)

Produktmerkmale:

• Recombinant human VPREB3 protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Reinheit: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Anwendungsinformationen

Applikationshinweise: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Kommentare:

The tag is located at the C-terminal.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Lagerung: -80 °C

Informationen zur Lagerung: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Antigendetails

Target: VPREB3 (Pre-B Lymphocyte 3 (VPREB3))

Andere Bezeichnung: Vpreb3 (VPREB3 Produkte)

Synonyme: 8HS-20 Protein, Vpreb-3 Protein, AI528709 Protein, VPREB3 Protein, 8HS20 Protein, N27C7-2 Protein, pre-B lymphocyte gene 3 Protein, V-set pre-B cell surrogate light chain 3 Protein, pre-B lymphocyte 3 Protein, Ig lambda-6 chain C region Protein, Vpreb3 Protein, VPREB3 Protein, LOC698694 Protein

Hintergrund: The protein encoded by this gene is the human ortholog of the mouse VpreB3 (8HS20) protein, is thought to be involved in B-cell maturation, and may play a role in assembly of the pre-B cell receptor (pre-BCR). While the role of this protein in B-cell development has not yet been elucidated, studies with the chicken ortholog of this protein have found that when overexpressed, this protein localizes to the endoplasmic reticulum. The mouse ortholog of this protein has been shown to associate with membrane mu heavy chains early in the course of pre-B cell receptor biosynthesis. Expression of this gene has been observed in some lymphomas.

Molekulargewicht: 13.5 kDa

NCBI Accession: NP_037510

Pathways: Production of Molecular Mediator of Immune Response