UGT2B15 Protein (Myc-DYKDDDDK Tag)

Produktnummer ABIN2734994

Produktdetails

Target: UGT2B15 (UDP Glucuronosyltransferase 2 Family, Polypeptide B15 (UGT2B15))

Protein-Typ: Recombinant

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses UGT2B15 Protein ist gelabelt mit Myc-DYKDDDDK Tag.

Applikation: Antibody Production (AbP), Standard (STD)

Produktmerkmale:

• Recombinant human UGT2B15 / UGT2B8 protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Reinheit: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Anwendungsinformationen

Applikationshinweise: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Kommentare:

The tag is located at the C-terminal.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Lagerung: -80 °C

Informationen zur Lagerung: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Referenzen

Divakaran, Hines, McCarver: "Human hepatic UGT2B15 developmental expression." in: Toxicological sciences : an official journal of the Society of Toxicology, Vol. 141, Issue 1, pp. 292-9, (2014) (PubMed).

Antigendetails

Target: UGT2B15 (UDP Glucuronosyltransferase 2 Family, Polypeptide B15 (UGT2B15))

Andere Bezeichnung: Ugt2b15,ugt2b8 (UGT2B15 Produkte)

Synonyme: UGT2B28 Protein, HLUG4 Protein, UDPGT 2B8 Protein, UDPGT2B15 Protein, UDPGTH3 Protein, UGT2B8 Protein, UDP-glucuronosyltransferase 2B15 Protein, UDP glucuronosyltransferase family 2 member B15 Protein, LOC461289 Protein, LOC100591991 Protein, UGT2B15 Protein

Hintergrund: UDPGTs are of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds. This isozyme displays activity toward several classes of xenobiotic substrates, including simple phenolic compounds, 7-hydroxylated coumarins, flavonoids, anthraquinones, and certain drugs and their hydroxylated metabolites. It also catalyzes the glucuronidation of endogenous estrogens and androgens. [UniProtKB/Swiss-Prot Function]

Molekulargewicht: 60.9 kDa

NCBI Accession: NP_001067

Pathways: Steroid Hormone Biosynthesis