UGT1A10 Protein (Myc-DYKDDDDK Tag)

Produktnummer ABIN2734989

Produktdetails

Target: UGT1A10 (UDP Glucuronosyltransferase 1 Family, Polypeptide A10 (UGT1A10))

Protein-Typ: Recombinant

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses UGT1A10 Protein ist gelabelt mit Myc-DYKDDDDK Tag.

Applikation: Antibody Production (AbP), Standard (STD)

Produktmerkmale:

• Recombinant human UGT1A10 protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Reinheit: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Anwendungsinformationen

Applikationshinweise: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Kommentare:

The tag is located at the C-terminal.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Lagerung: -80 °C

Informationen zur Lagerung: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Antigendetails

Target: UGT1A10 (UDP Glucuronosyltransferase 1 Family, Polypeptide A10 (UGT1A10))

Andere Bezeichnung: Ugt1a10 (UGT1A10 Produkte)

Synonyme: UDPGT Protein, UGT-1J Protein, UGT1-10 Protein, UGT1.10 Protein, UGT1J Protein, A13 Protein, Ugt1a13 Protein, UDP glucuronosyltransferase family 1 member A10 Protein, UDP glycosyltransferase 1 family, polypeptide A10 Protein, UGT1A10 Protein, Ugt1a10 Protein

Hintergrund: This gene encodes a UDP-glucuronosyltransferase, an enzyme of the glucuronidation pathway that transforms small lipophilic molecules, such as steroids, bilirubin, hormones, and drugs, into water-soluble, excretable metabolites. This gene is part of a complex locus that encodes several UDP-glucuronosyltransferases. The locus includes thirteen unique alternate first exons followed by four common exons. Four of the alternate first exons are considered pseudogenes. Each of the remaining nine 5&apos exons may be spliced to the four common exons, resulting in nine proteins with different N-termini and identical C-termini. Each first exon encodes the substrate binding site, and is regulated by its own promoter. The enzyme encoded by this gene has glucuronidase activity on mycophenolic acid, coumarins, and quinolines.

Molekulargewicht: 57.2 kDa

NCBI Accession: NP_061948

Pathways: Steroid Hormone Biosynthesis, Regulation of Lipid Metabolism by PPARalpha