Ubiquilin 1 Protein (UBQLN1) (Transcript Variant 2) (Myc-DYKDDDDK Tag)

Produktnummer ABIN2734885

Produktdetails

Target: Ubiquilin 1 (UBQLN1)

Protein-Typ: Recombinant

Proteineigenschaft: Transcript Variant 2

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses Ubiquilin 1 Protein ist gelabelt mit Myc-DYKDDDDK Tag.

Applikation: Antibody Production (AbP), Standard (STD)

Produktmerkmale:

• Recombinant human Ubiquilin-1 (UBQLN1) (transcript variant 2) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Reinheit: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Anwendungsinformationen

Applikationshinweise: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Kommentare:

The tag is located at the C-terminal.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Lagerung: -80 °C

Informationen zur Lagerung: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Antigendetails

Target: Ubiquilin 1 (UBQLN1)

Andere Bezeichnung: Ubiquilin-1 (Ubqln1) (UBQLN1 Produkte)

Synonyme: UBQLN1 Protein, DA41 Protein, DSK2 Protein, PLIC-1 Protein, UBQN Protein, XDRP1 Protein, 1110046H03Rik Protein, 1810030E05Rik Protein, AU019746 Protein, C77538 Protein, D13Ertd372e Protein, Da41 Protein, Dsk2 Protein, Plic-1 Protein, Plic1 Protein, Xdrp1 Protein, ubiquilin 1 Protein, UBQLN1 Protein, Ubqln1 Protein

Hintergrund: This gene encodes an ubiquitin-like protein (ubiquilin) that shares a high degree of similarity with related products in yeast, rat and frog. Ubiquilins contain an N-terminal ubiquitin-like domain and a C-terminal ubiquitin-associated domain. They physically associate with both proteasomes and ubiquitin ligases, and thus are thought to functionally link the ubiquitination machinery to the proteasome to affect in vivo protein degradation. This ubiquilin has also been shown to modulate accumulation of presenilin proteins, and it is found in lesions associated with Alzheimer&aposs and Parkinson&aposs disease. Two transcript variants encoding different isoforms have been found for this gene.

Molekulargewicht: 59 kDa

NCBI Accession: NP_444295