UBE4A Protein (Myc-DYKDDDDK Tag)

Produktnummer ABIN2734882

Produktdetails

Target: UBE4A (Ubiquitination Factor E4A (UBE4A))

Protein-Typ: Recombinant

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses UBE4A Protein ist gelabelt mit Myc-DYKDDDDK Tag.

Applikation: Antibody Production (AbP), Standard (STD)

Produktmerkmale:

• Recombinant human UBE4A protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Reinheit: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Anwendungsinformationen

Applikationshinweise: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Kommentare:

The tag is located at the C-terminal.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Lagerung: -80 °C

Informationen zur Lagerung: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Antigendetails

Target: UBE4A (Ubiquitination Factor E4A (UBE4A))

Andere Bezeichnung: Ube4a (UBE4A Produkte)

Synonyme: 4732444G18Rik Protein, 9930123J21Rik Protein, UFD2b Protein, ufd2 Protein, ubox2 Protein, E4 Protein, UBOX2 Protein, UFD2 Protein, Ab2-232 Protein, ubiquitination factor E4A S homeolog Protein, ubiquitination factor E4A Protein, ubiquitination factor E4A (UFD2 homolog, yeast) Protein, ubiquitin conjugation factor E4 A Protein, putative ubiquitination factor E4a Protein, ube4a.S Protein, Ube4a Protein, UBE4A Protein, ube4a Protein, LOC5563714 Protein, Smp_030780 Protein

Hintergrund: This gene encodes a member of the U-box ubiquitin ligase family. The encoded protein is involved in multiubiquitin chain assembly and plays a critical role in chromosome condensation and separation through the polyubiquitination of securin. Autoantibodies against the encoded protein may be markers for scleroderma and Crohn&aposs disease. A pseudogene of this gene is located on the long arm of chromosome 3. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Molekulargewicht: 123.3 kDa

NCBI Accession: NP_004779