Tumor Protein p73 Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)

Produktnummer ABIN2734636

Produktdetails

Target: Tumor Protein p73 (TP73) (Tumor Protein P73 (TP73))

Protein-Typ: Recombinant

Proteineigenschaft: Transcript Variant 1

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses Tumor Protein p73 Protein ist gelabelt mit Myc-DYKDDDDK Tag.

Applikation: Antibody Production (AbP), Standard (STD)

Produktmerkmale:

• Recombinant human Tumor protein p73 (TP73) (transcript variant 1) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Reinheit: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Anwendungsinformationen

Applikationshinweise: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Kommentare:

The tag is located at the C-terminal.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Lagerung: -80 °C

Informationen zur Lagerung: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Antigendetails

Target: Tumor Protein p73 (TP73) (Tumor Protein P73 (TP73))

Abstract: TP73 Produkte

Synonyme: P73 Protein, Trp73 Protein, TP73 Protein, tp73 Protein, Tp73 Protein, p73 Protein, TAp73 Protein, zp73theta Protein, tumor protein p73 Protein, transformation related protein 73 Protein, TP73 Protein, Tp73 Protein, tp73 Protein, Trp73 Protein

Hintergrund: This gene encodes a member of the p53 family of transcription factors involved in cellular responses to stress and development. It maps to a region on chromosome 1p36 that is frequently deleted in neuroblastoma and other tumors, and thought to contain multiple tumor suppressor genes. The demonstration that this gene is monoallelically expressed (likely from the maternal allele), supports the notion that it is a candidate gene for neuroblastoma. Many transcript variants resulting from alternative splicing and/or use of alternate promoters have been found for this gene, but the biological validity and the full-length nature of some variants have not been determined.

Molekulargewicht: 69.4 kDa

NCBI Accession: NP_005418

Pathways: Regulation of Cell Size, Positive Regulation of Response to DNA Damage Stimulus