IL27 Receptor alpha Protein (Myc-DYKDDDDK Tag)

Produktnummer ABIN2733333

Produktdetails

Target: IL27 Receptor alpha (IL27RA) (Interleukin 27 Receptor, alpha (IL27RA))

Protein-Typ: Recombinant

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses IL27 Receptor alpha Protein ist gelabelt mit Myc-DYKDDDDK Tag.

Applikation: Antibody Production (AbP), Standard (STD)

Produktmerkmale:

• Recombinant human TCCR / IL27RA protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Reinheit: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Anwendungsinformationen

Applikationshinweise: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Kommentare:

The tag is located at the C-terminal.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Lagerung: -80 °C

Informationen zur Lagerung: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Antigendetails

Target: IL27 Receptor alpha (IL27RA) (Interleukin 27 Receptor, alpha (IL27RA))

Andere Bezeichnung: Tccr,il27ra (IL27RA Produkte)

Synonyme: IL27RA Protein, CRL1 Protein, IL-27RA Protein, IL27R Protein, TCCR Protein, WSX1 Protein, zcytor1 Protein, IL-27R Protein, Tccr Protein, WSX-1 Protein, Wsx1 Protein, interleukin 27 receptor subunit alpha Protein, interleukin-27 receptor subunit alpha Protein, interleukin 27 receptor, alpha Protein, IL27RA Protein, LOC484907 Protein, Il27ra Protein

Hintergrund: In mice, CD4+ helper T-cells differentiate into type 1 (Th1) cells, which are critical for cell-mediated immunity, predominantly under the influence of IL12. Also, IL4 influences their differentiation into type 2 (Th2) cells, which are critical for most antibody responses. Mice deficient in these cytokines, their receptors, or associated transcription factors have impaired, but are not absent of, Th1 or Th2 immune responses. This gene encodes a protein which is similar to the mouse T-cell cytokine receptor Tccr at the amino acid level, and is predicted to be a glycosylated transmembrane protein.

Molekulargewicht: 69.3 kDa

NCBI Accession: NP_004834

Pathways: Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response