T-Box 1 Protein (TBX1) (Transcript Variant C) (Myc-DYKDDDDK Tag)

Produktnummer ABIN2733303

Produktdetails

Target: T-Box 1 (TBX1)

Protein-Typ: Recombinant

Proteineigenschaft: Transcript Variant C

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses T-Box 1 Protein ist gelabelt mit Myc-DYKDDDDK Tag.

Applikation: Antibody Production (AbP), Standard (STD)

Produktmerkmale:

• Recombinant human TBX1 (transcript variant C) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Reinheit: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Anwendungsinformationen

Applikationshinweise: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Kommentare:

The tag is located at the C-terminal.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Lagerung: -80 °C

Informationen zur Lagerung: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Antigendetails

Target: T-Box 1 (TBX1)

Andere Bezeichnung: Tbx1 (TBX1 Produkte)

Synonyme: CAFS Protein, CTHM Protein, DGCR Protein, DGS Protein, DORV Protein, TBX1C Protein, TGA Protein, VCFS Protein, mp:zf637-3-000616 Protein, zgc:136724 Protein, TBX1 Protein, dgs Protein, tga Protein, cafs Protein, cthm Protein, dgcr Protein, dorv Protein, vcfs Protein, tbx1c Protein, xtbx1 Protein, tbx1 Protein, T-box 1 Protein, T-box 1 S homeolog Protein, T-box 1 L homeolog Protein, TBX1 Protein, Tbx1 Protein, tbx1 Protein, tbx1.S Protein, tbx1.L Protein

Hintergrund: This gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. This gene product shares 98 % amino acid sequence identity with the mouse ortholog. DiGeorge syndrome (DGS)/velocardiofacial syndrome (VCFS), a common congenital disorder characterized by neural-crest-related developmental defects, has been associated with deletions of chromosome 22q11.2, where this gene has been mapped. Studies using mouse models of DiGeorge syndrome suggest a major role for this gene in the molecular etiology of DGS/VCFS. Several alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Molekulargewicht: 52.5 kDa

NCBI Accession: NP_542378

Pathways: Retinoic Acid Receptor Signaling Pathway, Sensory Perception of Sound, Cellular Response to Molecule of Bacterial Origin, Regulation of Muscle Cell Differentiation