TBL1XR1 Protein (His tag)

Produktnummer ABIN2733299

Produktdetails

Target: TBL1XR1 (Transducin (Beta)-Like 1 X-Linked Receptor 1 (TBL1XR1))

Protein-Typ: Recombinant

Spezies: Human

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses TBL1XR1 Protein ist gelabelt mit His tag.

Applikation: Antibody Production (AbP), Standard (STD)

Produktmerkmale:

• Recombinant human TBL1XR1 (full length, N-term HIS tag) protein expressed in E.coli.
• Produced with end-sequenced ORF clone

Reinheit: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Anwendungsinformationen

Applikationshinweise: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Kommentare:

The tag is located at the N-terminal.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 50 μg/mL

Buffer: 25 mM Tris, pH 8.0, 150 mM NaCl, 10 % glycerol, 1 % Sarkosyl.

Lagerung: -80 °C

Informationen zur Lagerung: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Antigendetails

Target: TBL1XR1 (Transducin (Beta)-Like 1 X-Linked Receptor 1 (TBL1XR1))

Andere Bezeichnung: Tbl1xr1 (TBL1XR1 Produkte)

Synonyme: tbl1xr1 Protein, zgc:63617 Protein, c21 Protein, dc42 Protein, ira1 Protein, TBLR1 Protein, TBL1XR1 Protein, wu:fc46g07 Protein, zgc:110312 Protein, C21 Protein, DC42 Protein, IRA1 Protein, RGD1560053 Protein, 8030499H02Rik Protein, A630076E03Rik Protein, AW539987 Protein, C230089I12Rik Protein, Ira1 Protein, transducin (beta)-like 1 X-linked receptor 1b Protein, transducin (beta)-like 1 X-linked receptor 1 Protein, transducin (beta)-like 1 X-linked receptor 1a Protein, transducin beta like 1 X-linked receptor 1 Protein, transducin (beta)-like 1X-linked receptor 1 Protein, tbl1xr1b Protein, tbl1xr1 Protein, tbl1xr1a Protein, TBL1XR1 Protein, Tbl1xr1 Protein

Hintergrund: This gene is a member of the WD40 repeat-containing gene family and shares sequence similarity with transducin (beta)-like 1X-linked (TBL1X). The protein encoded by this gene is thought to be a component of both nuclear receptor corepressor (N-CoR) and histone deacetylase 3 (HDAC 3) complexes, and is required for transcriptional activation by a variety of transcription factors. Mutations in these gene have been associated with some autism spectrum disorders, and one finding suggests that haploinsufficiency of this gene may be a cause of intellectual disability with dysmorphism. Mutations in this gene as well as recurrent translocations involving this gene have also been observed in some tumors.

Molekulargewicht: 55.4 kDa

NCBI Accession: NP_078941

Pathways: Regulation of Lipid Metabolism by PPARalpha